Gene: ENSG00000150630 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000150630
Transcript Identifier
ENST00000618562
Gene Type
Coding gene
Location
4 : 176683926-176792311 : negative

Family Information

Homologous gene family
HOM03P016811
(5 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P070911
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
vascular endothelial growth factor C

Identifiers

Type Value
pidENSP00000480043
HGNC12682
UniprotP49767

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001954
IEA
Genome Projectpositive regulation of cell-matrix adhesion
GO:0002052
IEA
Genome Projectpositive regulation of neuroblast proliferation
GO:0002576
TAS
Genome Projectplatelet degranulation
GO:0006929
TAS
Genome Projectsubstrate-dependent cell migration
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008284
TAS, IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009887
IEA
Genome Projectorgan morphogenesis
GO:0016331
IEA
Genome Projectmorphogenesis of embryonic epithelium
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030168
TAS
Genome Projectplatelet activation
GO:0030947
IEA
Genome Projectregulation of vascular endothelial growth factor receptor signaling pathway
GO:0031954
IEA
Genome Projectpositive regulation of protein autophosphorylation
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043536
IEA
Genome Projectpositive regulation of blood vessel endothelial cell migration
GO:0045766
IEA
Genome Projectpositive regulation of angiogenesis
GO:0045776
IEA
Genome Projectnegative regulation of blood pressure
GO:0048010
TAS, IEA
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0050679
IEA
Genome Projectpositive regulation of epithelial cell proliferation
GO:0050714
IEA
Genome Projectpositive regulation of protein secretion
GO:0050731
IEA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050918
IDA
Genome Projectpositive chemotaxis
GO:0050930
IDA
Genome Projectinduction of positive chemotaxis
GO:0051781
IEA
Genome Projectpositive regulation of cell division
GO:0060754
IDA
Genome Projectpositive regulation of mast cell chemotaxis
GO:1901492
IEA
Genome Projectpositive regulation of lymphangiogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008083
IEA
Genome Projectgrowth factor activity
GO:0042056
IDA
Genome Projectchemoattractant activity
GO:0043185
IEA
Genome Projectvascular endothelial growth factor receptor 3 binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IEA
Genome Projectextracellular space
GO:0016020
IEA
Genome Projectmembrane
GO:0031093
TAS
Genome Projectplatelet alpha granule lumen

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000072PDGF/VEGF domain
IPR004153CXCXC repeat
IPR023581Platelet-derived growth factor, conserved site
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.