Gene: ENSG00000150093 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000150093
Transcript Identifier
ENST00000423113
Gene Type
Coding gene
Location
10 : 32907069-32935558 : negative

Family Information

Homologous gene family
HOM03P005934
(15 genes in 4 species)
specific family

Descriptions

gene_descr
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Identifiers

Type Value
pidENSP00000388694
HGNC6153
UniprotP05556

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000082
IEA
Genome ProjectG1/S transition of mitotic cell cycle
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001708
IEA
Genome Projectcell fate specification
GO:0002042
IEA
Genome Projectcell migration involved in sprouting angiogenesis
GO:0006968
TAS
Genome Projectcellular defense response
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007156
TAS
Genome Projecthomophilic cell adhesion via plasma membrane adhesion molecules
GO:0007159
IDA
Genome Projectleukocyte cell-cell adhesion
GO:0007160
IMP
IEA
Genome Projectcell-matrix adhesion
GO:0007161
IGI
Genome Projectcalcium-independent cell-matrix adhesion
GO:0007229
IMP
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007411
TAS
Genome Projectaxon guidance
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008354
IEA
Genome Projectgerm cell migration
GO:0008542
IEA
Genome Projectvisual learning
GO:0010710
IDA
Genome Projectregulation of collagen catabolic process
GO:0016032
IEA
Genome Projectviral process
GO:0016477
TAS, IEA
Genome Projectcell migration
GO:0021943
IEA
Genome Projectformation of radial glial scaffolds
GO:0030183
IC
Genome ProjectB cell differentiation
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0031175
IEA
Genome Projectneuron projection development
GO:0031589
IMP
Genome Projectcell-substrate adhesion
GO:0033631
IEP
Genome Projectcell-cell adhesion mediated by integrin
GO:0034113
IMP
Genome Projectheterotypic cell-cell adhesion
GO:0034329
TAS
Genome Projectcell junction assembly
GO:0035024
IEA
Genome Projectnegative regulation of Rho protein signal transduction
GO:0043065
IGI
Genome Projectpositive regulation of apoptotic process
GO:0045214
IEA
Genome Projectsarcomere organization
GO:0045596
IEA
Genome Projectnegative regulation of cell differentiation
GO:0046718
IEA
Genome Projectviral entry into host cell
GO:0048333
IEP
Genome Projectmesodermal cell differentiation
GO:0048675
IEA
Genome Projectaxon extension
GO:0048738
IEA
Genome Projectcardiac muscle tissue development
GO:0048813
IEA
Genome Projectdendrite morphogenesis
GO:0050776
TAS
Genome Projectregulation of immune response
GO:0050900
TAS
Genome Projectleukocyte migration
GO:0050901
IMP
Genome Projectleukocyte tethering or rolling
GO:0051726
IEA
Genome Projectregulation of cell cycle
GO:0055007
IEA
Genome Projectcardiac muscle cell differentiation
GO:0090004
IDA
Genome Projectpositive regulation of establishment of protein localization to plasma membrane
GO:2000811
IMP
Genome Projectnegative regulation of anoikis
GO:0007179
IMP
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0043149
IMP
Genome Projectstress fiber assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001618
IEA
Genome Projectvirus receptor activity
GO:0001968
IPI
Genome Projectfibronectin binding
GO:0002020
IPI
Genome Projectprotease binding
GO:0003779
IDA
Genome Projectactin binding
GO:0004872
IEA
Genome Projectreceptor activity
GO:0005178
IEA
Genome Projectintegrin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043236
IEA
Genome Projectlaminin binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IDA
NAS
Genome Projectprotein heterodimerization activity
GO:0050839
IPI
Genome Projectcell adhesion molecule binding
GO:0098639
IMP
Genome Projectcollagen binding involved in cell-matrix adhesion

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001726
TAS, IEA
Genome Projectruffle
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005886
IDA
TAS, NAS, IEA
Genome Projectplasma membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0008305
NAS, IEA
Genome Projectintegrin complex
GO:0009897
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0014704
IEA
Genome Projectintercalated disc
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030027
IEA
Genome Projectlamellipodium
GO:0030054
IEA
Genome Projectcell junction
GO:0030175
IDA
Genome Projectfilopodium
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0031594
IDA
Genome Projectneuromuscular junction
GO:0032154
IEA
Genome Projectcleavage furrow
GO:0032587
IDA
NAS, IEA
Genome Projectruffle membrane
GO:0034665
IDA
Genome Projectintegrin alpha1-beta1 complex
GO:0034666
IDA
Genome Projectintegrin alpha2-beta1 complex
GO:0034667
IDA
Genome Projectintegrin alpha3-beta1 complex
GO:0034677
IEA
Genome Projectintegrin alpha7-beta1 complex
GO:0034678
TAS
Genome Projectintegrin alpha8-beta1 complex
GO:0034680
IDA
Genome Projectintegrin alpha10-beta1 complex
GO:0034681
IDA
Genome Projectintegrin alpha11-beta1 complex
GO:0035748
IEA
Genome Projectmyelin sheath abaxonal region
GO:0042383
IDA
IEA
Genome Projectsarcolemma
GO:0042470
IEA
Genome Projectmelanosome
GO:0042995
IEA
Genome Projectcell projection
GO:0043197
IEA
Genome Projectdendritic spine
GO:0043235
IDA
Genome Projectreceptor complex
GO:0045121
IDA
Genome Projectmembrane raft
GO:0045202
IEA
Genome Projectsynapse
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0055037
IEA
Genome Projectrecycling endosome
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0071438
IDA
IEA
Genome Projectinvadopodium membrane
GO:0097060
IEA
Genome Projectsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002035von Willebrand factor, type A
IPR002369Integrin beta subunit, N-terminal
IPR012896Integrin beta subunit, tail
IPR013111EGF-like domain, extracellular
IPR014836Integrin beta subunit, cytoplasmic domain
IPR015812Integrin beta subunit
IPR016201Plexin-like fold
IPR027071Integrin beta-1 subunit

No MapMan annotations defined for this gene.