Gene: ENSG00000149798 (Homo sapiens)

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Gene Identifier
ENSG00000149798
Transcript Identifier
ENST00000533419
Gene Type
Coding gene
Location
11 : 65320899-65321531 : positive

Family Information

Homologous gene family
HOM03P022596
(4 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P071773
(2 genes in 2 species)
specific family

Descriptions

gene_descr
CDC42 effector protein (Rho GTPase binding) 2

Identifiers

Type Value
pidENSP00000431660
HGNC16263
UniprotO14613

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007015
NAS
Genome Projectactin filament organization
GO:0007266
IBA
Genome ProjectRho protein signal transduction
GO:0008360
IDA
IEA
Genome Projectregulation of cell shape
GO:0030036
IDA
Genome Projectactin cytoskeleton organization
GO:0030838
IDA
Genome Projectpositive regulation of actin filament polymerization
GO:0031274
IDA
Genome Projectpositive regulation of pseudopodium assembly
GO:0031334
TAS
Genome Projectpositive regulation of protein complex assembly
GO:0043547
IMP
Genome Projectpositive regulation of GTPase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001515
IEA
Genome Projectopioid peptide activity
GO:0005096
IMP
Genome ProjectGTPase activator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0017049
IPI
Genome ProjectGTP-Rho binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IDA
Genome Projectplasma membrane
GO:0012505
IEA
Genome Projectendomembrane system
GO:0015630
IDA
Genome Projectmicrotubule cytoskeleton
GO:0016020
IDA
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000095CRIB domain
IPR017363Cdc42 effector protein 2
IPR029273Cdc42 effector

No MapMan annotations defined for this gene.