Gene: ENSG00000149305 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000149305
Transcript Identifier
ENST00000260191
Gene Type
Coding gene
Location
11 : 113904934-113946137 : positive

Family Information

Homologous gene family
HOM03P000517
(94 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P073095
(2 genes in 2 species)
specific family

Descriptions

gene_descr
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic

Identifiers

Type Value
pidENSP00000260191
HGNC5298
UniprotO95264

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006810
TAS, IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006812
IEA
Genome Projectcation transport
GO:0007210
IBA
IEA
Genome Projectserotonin receptor signaling pathway
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0034220
TAS
Genome Projection transmembrane transport
GO:0042391
IBA
Genome Projectregulation of membrane potential
GO:0050877
IBA
Genome Projectneurological system process
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0098655
IBA
IEA
Genome Projectcation transmembrane transport
GO:0007271
IBA
Genome Projectsynaptic transmission, cholinergic
GO:0007274
IBA
Genome Projectneuromuscular synaptic transmission
GO:0035094
IBA
Genome Projectresponse to nicotine

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004993
TAS, IEA
Genome Projectserotonin receptor activity
GO:0005216
TAS
Genome Projection channel activity
GO:0005230
IEA
Genome Projectextracellular ligand-gated ion channel activity
GO:0005232
TAS, IEA
Genome Projectserotonin-activated cation-selective channel activity
GO:0015276
IEA
Genome Projectligand-gated ion channel activity
GO:0004889
IBA
Genome Projectacetylcholine-activated cation-selective channel activity
GO:0015464
IBA
Genome Projectacetylcholine receptor activity
GO:0042166
IBA
Genome Projectacetylcholine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS, IEA
Genome Projectintegral component of plasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0043005
IBA
Genome Projectneuron projection
GO:0045202
IBA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0005892
IBA
Genome Projectacetylcholine-gated channel complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006029Neurotransmitter-gated ion-channel transmembrane domain
IPR006201Neurotransmitter-gated ion-channel
IPR006202Neurotransmitter-gated ion-channel ligand-binding domain
IPR0081325-hydroxytryptamine 3 receptor
IPR0081345-hydroxytryptamine 3 receptor, B subunit
IPR027361Nicotinic acetylcholine-gated receptor, transmembrane domain

No MapMan annotations defined for this gene.