Gene: ENSG00000146701 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000146701
Transcript Identifier
ENST00000315758
Gene Type
Coding gene
Location
7 : 76048161-76066410 : positive

Family Information

Homologous gene family
HOM03P000505
(96 genes in 34 species)
specific family
Orthologous gene family
ORTHO03P001102
(40 genes in 35 species)
specific family

Descriptions

gene_descr
malate dehydrogenase 2, NAD (mitochondrial)

Identifiers

Type Value
pidENSP00000327070
HGNC6971
UniprotP40926
UniprotA0A024R4K3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005975
TAS, IEA
Genome Projectcarbohydrate metabolic process
GO:0006099
TAS, IEA
Genome Projecttricarboxylic acid cycle
GO:0006107
IEA
Genome Projectoxaloacetate metabolic process
GO:0006108
IDA, IMP
IEA
Genome Projectmalate metabolic process
GO:0006734
IEA
Genome ProjectNADH metabolic process
GO:0019752
IEA
Genome Projectcarboxylic acid metabolic process
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0006006
TAS
Genome Projectglucose metabolic process
GO:0006094
TAS
Genome Projectgluconeogenesis
GO:0006475
IDA
Genome Projectinternal protein amino acid acetylation
GO:0044237
TAS
Genome Projectcellular metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016615
IEA
Genome Projectmalate dehydrogenase activity
GO:0016616
IEA
Genome Projectoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030060
EXP, IDA, IMP
IEA
Genome ProjectL-malate dehydrogenase activity
GO:0043621
IEA
Genome Projectprotein self-association
GO:0046554
IEA
Genome Projectmalate dehydrogenase (NADP+) activity
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005743
IEA
Genome Projectmitochondrial inner membrane
GO:0005759
TAS, IEA
Genome Projectmitochondrial matrix
GO:0016020
IEA
Genome Projectmembrane
GO:0043209
IEA
Genome Projectmyelin sheath
GO:0005634
IDA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005886
IDA
Genome Projectplasma membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001236Lactate/malate dehydrogenase, N-terminal
IPR001252Malate dehydrogenase, active site
IPR001557L-lactate/malate dehydrogenase
IPR010097Malate dehydrogenase, type 1
IPR015955Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR016040NAD(P)-binding domain
IPR022383Lactate/malate dehydrogenase, C-terminal

No MapMan annotations defined for this gene.