Gene: ENSG00000146247 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000146247
Transcript Identifier
ENST00000275034
Gene Type
Coding gene
Location
6 : 78940693-79078068 : negative

Family Information

Homologous gene family
HOM03P000003
(2229 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P012283
(7 genes in 3 species)
specific family

Descriptions

gene_descr
pleckstrin homology domain interacting protein

Identifiers

Type Value
pidENSP00000275034
HGNC15673
UniprotQ8WWQ0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001932
ISS
Genome Projectregulation of protein phosphorylation
GO:0006606
IEA
Genome Projectprotein import into nucleus
GO:0007010
IMP
Genome Projectcytoskeleton organization
GO:0008284
ISS
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008286
NAS, IEA
Genome Projectinsulin receptor signaling pathway
GO:0008360
IBA
Genome Projectregulation of cell shape
GO:0010800
IEA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0022604
IMP
Genome Projectregulation of cell morphogenesis
GO:0033138
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0040008
IEA
Genome Projectregulation of growth
GO:0043066
ISS
Genome Projectnegative regulation of apoptotic process
GO:0043568
ISS
Genome Projectpositive regulation of insulin-like growth factor receptor signaling pathway
GO:0045840
ISS
Genome Projectpositive regulation of mitotic nuclear division
GO:0045893
ISS
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:2001237
IDA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005158
NAS, IEA
Genome Projectinsulin receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0070577
IDA
Genome Projectlysine-acetylated histone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISS, IBA
IEA
Genome Projectnucleus
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001487Bromodomain
IPR001680WD40 repeat
IPR015943WD40/YVTN repeat-like-containing domain
IPR017986WD40-repeat-containing domain
IPR018359Bromodomain, conserved site
IPR019775WD40 repeat, conserved site
IPR028738PH-interacting protein

No MapMan annotations defined for this gene.