Gene: ENSG00000146072 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000146072
Transcript Identifier
ENST00000296861
Gene Type
Coding gene
Location
6 : 47232765-47309511 : negative

Family Information

Homologous gene family
HOM03P025699
(3 genes in 2 species)
specific family

Descriptions

gene_descr
tumor necrosis factor receptor superfamily, member 21

Identifiers

Type Value
pidENSP00000296861
HGNC13469
UniprotO75509
UniprotA0A024RD71

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001783
ISS
IEA
Genome ProjectB cell apoptotic process
GO:0002250
ISS
IEA
Genome Projectadaptive immune response
GO:0006959
ISS
IEA
Genome Projecthumoral immune response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0030889
ISS
IEA
Genome Projectnegative regulation of B cell proliferation
GO:0042130
ISS
IEA
Genome Projectnegative regulation of T cell proliferation
GO:0042552
ISS
IEA
Genome Projectmyelination
GO:0048713
ISS
IEA
Genome Projectregulation of oligodendrocyte differentiation
GO:0050852
ISS
IEA
Genome ProjectT cell receptor signaling pathway
GO:0051402
ISS
IEA
Genome Projectneuron apoptotic process
GO:0097252
ISS
IEA
Genome Projectoligodendrocyte apoptotic process
GO:2000663
ISS
IEA
Genome Projectnegative regulation of interleukin-5 secretion
GO:2000666
ISS
IEA
Genome Projectnegative regulation of interleukin-13 secretion
GO:2001180
ISS
IEA
Genome Projectnegative regulation of interleukin-10 secretion
GO:0002376
IEA
Genome Projectimmune system process
GO:0006915
IMP
IEA
Genome Projectapoptotic process
GO:0031642
IMP
Genome Projectnegative regulation of myelination
GO:0044255
TAS
Genome Projectcellular lipid metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0071356
IDA
Genome Projectcellular response to tumor necrosis factor

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030424
IEA
Genome Projectaxon
GO:0031226
ISS
IEA
Genome Projectintrinsic component of plasma membrane
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IDA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000488Death domain
IPR001368TNFR/NGFR cysteine-rich region
IPR011029Death-like domain
IPR022330Tumour necrosis factor receptor 21

No MapMan annotations defined for this gene.