Gene: ENSG00000145362 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000145362
Transcript Identifier
ENST00000357077
Gene Type
Coding gene
Location
4 : 113049729-113381471 : positive

Family Information

Homologous gene family
HOM03P000010
(1560 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P002545
(29 genes in 13 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
ankyrin 2, neuronal

Identifiers

Type Value
pidENSP00000349588
HGNC493
UniprotQ01484

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002027
IMP
IEA
Genome Projectregulation of heart rate
GO:0003283
IMP
Genome Projectatrial septum development
GO:0006874
ISS
IEA
Genome Projectcellular calcium ion homeostasis
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007411
TAS
Genome Projectaxon guidance
GO:0008104
IEA
Genome Projectprotein localization
GO:0010628
IGI
IEA
Genome Projectpositive regulation of gene expression
GO:0010881
IGI
ISS
Genome Projectregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010882
IMP
IEA
Genome Projectregulation of cardiac muscle contraction by calcium ion signaling
GO:0031647
IC
Genome Projectregulation of protein stability
GO:0033292
ISS
IEA
Genome ProjectT-tubule organization
GO:0033365
IGI
Genome Projectprotein localization to organelle
GO:0034394
ISS
IEA
Genome Projectprotein localization to cell surface
GO:0034613
IGI
IEA
Genome Projectcellular protein localization
GO:0036309
ISS
IEA
Genome Projectprotein localization to M-band
GO:0036371
ISS
IEA
Genome Projectprotein localization to T-tubule
GO:0043268
ISS
IEA
Genome Projectpositive regulation of potassium ion transport
GO:0050821
ISS
IEA
Genome Projectprotein stabilization
GO:0051279
IGI
Genome Projectregulation of release of sequestered calcium ion into cytosol
GO:0051924
IGI
IEA
Genome Projectregulation of calcium ion transport
GO:0051928
ISS
IEA
Genome Projectpositive regulation of calcium ion transport
GO:0055117
IMP
IEA
Genome Projectregulation of cardiac muscle contraction
GO:0060048
IEA
Genome Projectcardiac muscle contraction
GO:0060307
IMP
Genome Projectregulation of ventricular cardiac muscle cell membrane repolarization
GO:0070296
TAS
Genome Projectsarcoplasmic reticulum calcium ion transport
GO:0070972
IGI
IEA
Genome Projectprotein localization to endoplasmic reticulum
GO:0072659
IGI
ISS
IEA
Genome Projectprotein localization to plasma membrane
GO:0072661
IEA
Genome Projectprotein targeting to plasma membrane
GO:0086004
IGI
IEA
Genome Projectregulation of cardiac muscle cell contraction
GO:0086005
IMP
Genome Projectventricular cardiac muscle cell action potential
GO:0086014
IMP
IEA
Genome Projectatrial cardiac muscle cell action potential
GO:0086015
ISS
IEA
Genome ProjectSA node cell action potential
GO:0086036
IEA
Genome Projectregulation of cardiac muscle cell membrane potential
GO:0086046
TAS
Genome Projectmembrane depolarization during SA node cell action potential
GO:0086066
ISS
IEA
Genome Projectatrial cardiac muscle cell to AV node cell communication
GO:0086070
IMP
IEA
Genome ProjectSA node cell to atrial cardiac muscle cell communication
GO:0086091
IMP
ISS
IEA
Genome Projectregulation of heart rate by cardiac conduction
GO:0098904
IEA
Genome Projectregulation of AV node cell action potential
GO:0098907
IMP
IEA
Genome Projectregulation of SA node cell action potential
GO:0098910
IMP
IEA
Genome Projectregulation of atrial cardiac muscle cell action potential
GO:1901018
ISS
IEA
Genome Projectpositive regulation of potassium ion transmembrane transporter activity
GO:1901019
ISS
IEA
Genome Projectregulation of calcium ion transmembrane transporter activity
GO:1901021
ISS
IEA
Genome Projectpositive regulation of calcium ion transmembrane transporter activity
GO:2001257
IEA
Genome Projectregulation of cation channel activity
GO:2001259
ISS
IEA
Genome Projectpositive regulation of cation channel activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0015459
IEA
Genome Projectpotassium channel regulator activity
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0030507
IPI
Genome Projectspectrin binding
GO:0030674
ISS
IEA
Genome Projectprotein binding, bridging
GO:0044325
IPI
ISS
IEA
Genome Projection channel binding
GO:0051117
ISS
IEA
Genome ProjectATPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IGI
IEA
Genome Projectintracellular
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
ISS
IEA
Genome Projectplasma membrane
GO:0005887
IEA
Genome Projectintegral component of plasma membrane
GO:0014704
ISS
IEA
Genome Projectintercalated disc
GO:0016020
IEA
Genome Projectmembrane
GO:0016323
IDA
Genome Projectbasolateral plasma membrane
GO:0016324
IEA
Genome Projectapical plasma membrane
GO:0030018
ISS
IEA
Genome ProjectZ disc
GO:0030054
IEA
Genome Projectcell junction
GO:0030315
ISS
IEA
Genome ProjectT-tubule
GO:0031430
ISS
IEA
Genome ProjectM band
GO:0031672
ISS
IEA
Genome ProjectA band
GO:0042383
ISS
IEA
Genome Projectsarcolemma
GO:0043034
ISS
IEA
Genome Projectcostamere
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0097481
IEA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000488Death domain
IPR000906ZU5 domain
IPR002110Ankyrin repeat
IPR011029Death-like domain
IPR020683Ankyrin repeat-containing domain
IPR030301Ankyrin-B

No MapMan annotations defined for this gene.