Gene: ENSG00000143839 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000143839
Transcript Identifier
ENST00000272190
Gene Type
Coding gene
Location
1 : 204155016-204166293 : negative

Family Information

Homologous gene family
HOM03P000232
(154 genes in 35 species)
specific family
Orthologous gene family
ORTHO03P070139
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
renin

Identifiers

Type Value
pidENSP00000272190
HGNC9958
UniprotP00797

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001822
IMP
Genome Projectkidney development
GO:0001823
IEA
Genome Projectmesonephros development
GO:0002003
IDA
TAS, IEA
Genome Projectangiotensin maturation
GO:0002016
IEA
Genome Projectregulation of blood volume by renin-angiotensin
GO:0002018
IEA
Genome Projectrenin-angiotensin regulation of aldosterone production
GO:0006508
IDA
IEA
Genome Projectproteolysis
GO:0008217
TAS
Genome Projectregulation of blood pressure
GO:0008584
IEA
Genome Projectmale gonad development
GO:0009755
IEA
Genome Projecthormone-mediated signaling pathway
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0035690
IEA
Genome Projectcellular response to drug
GO:0035902
IEA
Genome Projectresponse to immobilization stress
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042756
IEA
Genome Projectdrinking behavior
GO:0043408
IDA
Genome Projectregulation of MAPK cascade
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0048469
IEA
Genome Projectcell maturation
GO:0050435
IEA
Genome Projectbeta-amyloid metabolic process
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0070305
IEA
Genome Projectresponse to cGMP
GO:0030163
IBA
Genome Projectprotein catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004175
IEA
Genome Projectendopeptidase activity
GO:0004190
EXP, IDA
IEA
Genome Projectaspartic-type endopeptidase activity
GO:0005102
IPI
IEA
Genome Projectreceptor binding
GO:0005159
IEA
Genome Projectinsulin-like growth factor receptor binding
GO:0008233
IDA
IEA
Genome Projectpeptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005622
IEA
Genome Projectintracellular
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005764
IBA
Genome Projectlysosome
GO:0005886
TAS
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001461Aspartic peptidase
IPR001969Aspartic peptidase, active site
IPR012848Aspartic peptidase, N-terminal
IPR021109Aspartic peptidase domain

No MapMan annotations defined for this gene.