Gene: ENSG00000143761 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000143761
Transcript Identifier
ENST00000541182
Gene Type
Coding gene
Location
1 : 228097115-228098013 : positive

Family Information

Homologous gene family
HOM03P000048
(508 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000228
(60 genes in 36 species)
specific family

Descriptions

gene_descr
ADP-ribosylation factor 1

Identifiers

Type Value
pidENSP00000440005
HGNC652
UniprotP84077
UniprotA0A024R3Q3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007264
IEA
Genome Projectsmall GTPase mediated signal transduction
GO:0016192
IEA
Genome Projectvesicle-mediated transport
GO:0002090
ISS
Genome Projectregulation of receptor internalization
GO:0006644
TAS
Genome Projectphospholipid metabolic process
GO:0006661
TAS
Genome Projectphosphatidylinositol biosynthetic process
GO:0006810
IEA
Genome Projecttransport
GO:0006878
IMP
Genome Projectcellular copper ion homeostasis
GO:0006890
TAS
Genome Projectretrograde vesicle-mediated transport, Golgi to ER
GO:0006892
TAS
Genome Projectpost-Golgi vesicle-mediated transport
GO:0015031
IEA
Genome Projectprotein transport
GO:0016032
TAS
Genome Projectviral process
GO:0019886
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0034315
ISS
Genome Projectregulation of Arp2/3 complex-mediated actin nucleation
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0048205
TAS
Genome ProjectCOPI coating of Golgi vesicle
GO:0050690
TAS
Genome Projectregulation of defense response to virus by virus
GO:0060292
ISS
Genome Projectlong term synaptic depression
GO:0061024
TAS
Genome Projectmembrane organization
GO:0097061
ISS
Genome Projectdendritic spine organization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0005525
IEA
Genome ProjectGTP binding
GO:0003924
TAS
Genome ProjectGTPase activity
GO:0005057
TAS
Genome Projectreceptor signaling protein activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0012505
IEA
Genome Projectendomembrane system
GO:0030017
IEA
Genome Projectsarcomere
GO:0000139
TAS
Genome ProjectGolgi membrane
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0030054
IEA
Genome Projectcell junction
GO:0031252
IDA
Genome Projectcell leading edge
GO:0043005
IEA
Genome Projectneuron projection
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005225Small GTP-binding protein domain
IPR006689Small GTPase superfamily, ARF/SAR type
IPR024156Small GTPase superfamily, ARF type
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.