Gene: ENSG00000143507 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000143507
Transcript Identifier
ENST00000366899
Gene Type
Coding gene
Location
1 : 221702412-221739744 : negative

Family Information

Homologous gene family
HOM03P000093
(285 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P075413
(2 genes in 2 species)
specific family

Descriptions

gene_descr
dual specificity phosphatase 10

Identifiers

Type Value
pidENSP00000355866
HGNC3065
UniprotQ9Y6W6

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000188
IDA
Genome Projectinactivation of MAPK activity
GO:0002819
IEA
Genome Projectregulation of adaptive immune response
GO:0006470
IDA
TAS, IEA
Genome Projectprotein dephosphorylation
GO:0006950
TAS
Genome Projectresponse to stress
GO:0007254
TAS
Genome ProjectJNK cascade
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0016311
IEA
Genome Projectdephosphorylation
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032873
IEA
Genome Projectnegative regulation of stress-activated MAPK cascade
GO:0035335
IEA
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0043508
IBA
IEA
Genome Projectnegative regulation of JUN kinase activity
GO:0044387
IEA
Genome Projectnegative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045088
IEA
Genome Projectregulation of innate immune response
GO:0046329
IEA
Genome Projectnegative regulation of JNK cascade
GO:0048709
IEA
Genome Projectoligodendrocyte differentiation
GO:0048715
IEA
Genome Projectnegative regulation of oligodendrocyte differentiation
GO:0060266
IEA
Genome Projectnegative regulation of respiratory burst involved in inflammatory response
GO:0090335
IEA
Genome Projectregulation of brown fat cell differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004721
TAS, IEA
Genome Projectphosphoprotein phosphatase activity
GO:0004725
IEA
Genome Projectprotein tyrosine phosphatase activity
GO:0008138
IBA
IEA
Genome Projectprotein tyrosine/serine/threonine phosphatase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016791
IDA
IEA
Genome Projectphosphatase activity
GO:0017017
IEA
Genome ProjectMAP kinase tyrosine/serine/threonine phosphatase activity
GO:0033549
IDA
Genome ProjectMAP kinase phosphatase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
TAS, IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
TAS, IEA
Genome Projectcytoplasm
GO:0005794
IDA
Genome ProjectGolgi apparatus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000340Dual specificity phosphatase, catalytic domain
IPR000387Tyrosine specific protein phosphatases domain
IPR001763Rhodanese-like domain
IPR008343Mitogen-activated protein (MAP) kinase phosphatase
IPR016130Protein-tyrosine phosphatase, active site
IPR020417Atypical dual specificity phosphatase
IPR020422Dual specificity protein phosphatase domain
IPR024950Dual specificity phosphatase
IPR029021Protein-tyrosine phosphatase-like

No MapMan annotations defined for this gene.