Gene: ENSG00000143185 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000143185
Transcript Identifier
ENST00000367819
Gene Type
Coding gene
Location
1 : 168540952-168543964 : negative

Family Information

Homologous gene family
HOM03P024547
(3 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C motif) ligand 2

Identifiers

Type Value
pidENSP00000356793
HGNC10646
UniprotQ9UBD3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002548
IBA
Genome Projectmonocyte chemotaxis
GO:0006935
IEA
Genome Projectchemotaxis
GO:0006954
IBA
Genome Projectinflammatory response
GO:0006955
IEA
Genome Projectimmune response
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007186
IBA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0008015
TAS
Genome Projectblood circulation
GO:0010820
IBA
Genome Projectpositive regulation of T cell chemotaxis
GO:0030593
IBA
Genome Projectneutrophil chemotaxis
GO:0043547
IBA
Genome Projectpositive regulation of GTPase activity
GO:0070098
IBA
Genome Projectchemokine-mediated signaling pathway
GO:0070374
IBA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071346
IBA
Genome Projectcellular response to interferon-gamma
GO:0071347
IBA
Genome Projectcellular response to interleukin-1
GO:0071356
IBA
Genome Projectcellular response to tumor necrosis factor

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008009
TAS, IEA
Genome Projectchemokine activity
GO:0048020
IBA
Genome ProjectCCR chemokine receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IBA
IEA
Genome Projectextracellular space

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001811Chemokine interleukin-8-like domain
IPR008105C chemokine ligand 1

No MapMan annotations defined for this gene.