Gene: ENSG00000143184 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000143184
Transcript Identifier
ENST00000367818
Gene Type
Coding gene
Location
1 : 168576638-168581220 : positive

Family Information

Homologous gene family
HOM03P024547
(3 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C motif) ligand 1

Identifiers

Type Value
pidENSP00000356792
HGNC10645
UniprotP47992

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001916
IDA
Genome Projectpositive regulation of T cell mediated cytotoxicity
GO:0002548
IBA
Genome Projectmonocyte chemotaxis
GO:0002690
ISS
Genome Projectpositive regulation of leukocyte chemotaxis
GO:0002725
IDA
Genome Projectnegative regulation of T cell cytokine production
GO:0002726
ISS
Genome Projectpositive regulation of T cell cytokine production
GO:0002826
IC
Genome Projectnegative regulation of T-helper 1 type immune response
GO:0006935
IEA
Genome Projectchemotaxis
GO:0006955
IEA
Genome Projectimmune response
GO:0007165
IC
Genome Projectsignal transduction
GO:0007186
IBA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007267
IDA
Genome Projectcell-cell signaling
GO:0009615
IDA
Genome Projectresponse to virus
GO:0010820
IDA
Genome Projectpositive regulation of T cell chemotaxis
GO:0030593
TAS
Genome Projectneutrophil chemotaxis
GO:0032689
IDA
Genome Projectnegative regulation of interferon-gamma production
GO:0032703
IDA
Genome Projectnegative regulation of interleukin-2 production
GO:0032733
IDA
Genome Projectpositive regulation of interleukin-10 production
GO:0035782
IDA
Genome Projectmature natural killer cell chemotaxis
GO:0043433
IDA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0043547
IBA
Genome Projectpositive regulation of GTPase activity
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0050727
IDA
Genome Projectregulation of inflammatory response
GO:0051209
ISS
Genome Projectrelease of sequestered calcium ion into cytosol
GO:0051281
IDA
Genome Projectpositive regulation of release of sequestered calcium ion into cytosol
GO:0070098
IBA
Genome Projectchemokine-mediated signaling pathway
GO:0070374
IBA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071346
IBA
Genome Projectcellular response to interferon-gamma
GO:0071347
IBA
Genome Projectcellular response to interleukin-1
GO:0071353
ISS
Genome Projectcellular response to interleukin-4
GO:0071356
IBA
Genome Projectcellular response to tumor necrosis factor
GO:0071560
ISS
Genome Projectcellular response to transforming growth factor beta stimulus
GO:0071636
IDA
Genome Projectpositive regulation of transforming growth factor beta production
GO:0071663
IDA
Genome Projectpositive regulation of granzyme B production
GO:0090023
ISS
Genome Projectpositive regulation of neutrophil chemotaxis
GO:2000412
ISS
Genome Projectpositive regulation of thymocyte migration
GO:2000503
IDA
Genome Projectpositive regulation of natural killer cell chemotaxis
GO:2000513
IDA
Genome Projectpositive regulation of granzyme A production
GO:2000518
IDA
Genome Projectnegative regulation of T-helper 1 cell activation
GO:2000538
ISS
Genome Projectpositive regulation of B cell chemotaxis
GO:2000553
ISS
Genome Projectpositive regulation of T-helper 2 cell cytokine production
GO:2000556
ISS
Genome Projectpositive regulation of T-helper 1 cell cytokine production
GO:2000558
ISS
Genome Projectpositive regulation of immunoglobulin production in mucosal tissue
GO:2000562
IDA
Genome Projectnegative regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000563
ISS
Genome Projectpositive regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000566
IDA
Genome Projectpositive regulation of CD8-positive, alpha-beta T cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IEA
Genome Projectcytokine activity
GO:0008009
IDA
IEA
Genome Projectchemokine activity
GO:0042379
IDA
NAS
Genome Projectchemokine receptor binding
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0048020
IBA
Genome ProjectCCR chemokine receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
ISS, IBA
IEA
Genome Projectextracellular space
GO:0005622
ISS
Genome Projectintracellular

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001811Chemokine interleukin-8-like domain
IPR008105C chemokine ligand 1

No MapMan annotations defined for this gene.