Gene: ENSG00000142875 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000142875
Transcript Identifier
ENST00000370685
Gene Type
Coding gene
Location
1 : 84144362-84235305 : positive

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000331
(54 genes in 23 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
protein kinase, cAMP-dependent, catalytic, beta

Identifiers

Type Value
pidENSP00000359719
HGNC9381
UniprotP22694

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001843
IEA
Genome Projectneural tube closure
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0003091
TAS
Genome Projectrenal water homeostasis
GO:0005975
TAS
Genome Projectcarbohydrate metabolic process
GO:0006006
TAS
Genome Projectglucose metabolic process
GO:0006094
TAS
Genome Projectgluconeogenesis
GO:0006112
TAS
Genome Projectenergy reserve metabolic process
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0006833
TAS
Genome Projectwater transport
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007188
TAS
Genome Projectadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007202
TAS
Genome Projectactivation of phospholipase C activity
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008543
TAS
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0019433
TAS
Genome Projecttriglyceride catabolic process
GO:0034199
TAS
Genome Projectactivation of protein kinase A activity
GO:0035556
TAS
Genome Projectintracellular signal transduction
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0050796
TAS
Genome Projectregulation of insulin secretion
GO:0051447
IEA
Genome Projectnegative regulation of meiotic cell cycle
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0070613
IEA
Genome Projectregulation of protein processing
GO:0071377
TAS
Genome Projectcellular response to glucagon stimulus
GO:0097338
IEA
Genome Projectresponse to clozapine
GO:1901621
IEA
Genome Projectnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0000287
IDA
Genome Projectmagnesium ion binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004691
IDA
TAS, IEA
Genome ProjectcAMP-dependent protein kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IDA
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0031625
IDA
Genome Projectubiquitin protein ligase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005813
IDA
Genome Projectcentrosome
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005952
TAS, IEA
Genome ProjectcAMP-dependent protein kinase complex
GO:0016020
IEA
Genome Projectmembrane
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0097546
TAS, IEA
Genome Projectciliary base

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.