Gene: ENSG00000142867 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000142867
Transcript Identifier
ENST00000370580
Gene Type
Coding gene
Location
1 : 85267627-85276352 : negative

Family Information

Homologous gene family
HOM03P117256
(orphan gene)
specific family

Descriptions

gene_descr
B-cell CLL/lymphoma 10

Identifiers

Type Value
pidENSP00000359612
HGNC989
UniprotO95999

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001783
IEA
Genome ProjectB cell apoptotic process
GO:0001843
ISS
IEA
Genome Projectneural tube closure
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0002224
IC
Genome Projecttoll-like receptor signaling pathway
GO:0002237
IEP
Genome Projectresponse to molecule of bacterial origin
GO:0002250
IMP
TAS
Genome Projectadaptive immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0002906
IDA
Genome Projectnegative regulation of mature B cell apoptotic process
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006968
IEA
Genome Projectcellular defense response
GO:0008219
IDA
Genome Projectcell death
GO:0009620
IEA
Genome Projectresponse to fungus
GO:0016064
IEA
Genome Projectimmunoglobulin mediated immune response
GO:0031398
IDA
Genome Projectpositive regulation of protein ubiquitination
GO:0032094
IDA
Genome Projectresponse to food
GO:0032765
NAS
Genome Projectpositive regulation of mast cell cytokine production
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0042109
NAS
Genome Projectlymphotoxin A biosynthetic process
GO:0042226
NAS
Genome Projectinterleukin-6 biosynthetic process
GO:0042327
IDA
Genome Projectpositive regulation of phosphorylation
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043123
IEP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280
IEA
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087
IEP
TAS
Genome Projectinnate immune response
GO:0045416
IMP
Genome Projectpositive regulation of interleukin-8 biosynthetic process
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0050852
IDA
TAS
Genome ProjectT cell receptor signaling pathway
GO:0050856
IEA
Genome Projectregulation of T cell receptor signaling pathway
GO:0050870
IEA
Genome Projectpositive regulation of T cell activation
GO:0051092
IDA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051259
IPI
Genome Projectprotein oligomerization
GO:0051260
ISS
TAS, IEA
Genome Projectprotein homooligomerization
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0070231
IEA
Genome ProjectT cell apoptotic process
GO:0071260
IEP
Genome Projectcellular response to mechanical stimulus
GO:2001238
IDA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
IPI
Genome Projectprotease binding
GO:0003713
IDA
Genome Projecttranscription coactivator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019900
IPI
Genome Projectkinase binding
GO:0019901
IDA
Genome Projectprotein kinase binding
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0043130
IDA
Genome Projectubiquitin binding
GO:0043422
IPI
Genome Projectprotein kinase B binding
GO:0043621
IPI
Genome Projectprotein self-association
GO:0051059
IDA
Genome ProjectNF-kappaB binding
GO:0019209
IDA
Genome Projectkinase activator activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
IEA
Genome Projectimmunological synapse
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005764
IDA
Genome Projectlysosome
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005881
IDA
Genome Projectcytoplasmic microtubule
GO:0005886
TAS
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0032449
NAS
Genome ProjectCBM complex
GO:0043234
IDA
Genome Projectprotein complex
GO:0045121
IEA
Genome Projectmembrane raft
GO:0048471
IDA
IEA
Genome Projectperinuclear region of cytoplasm
GO:0042101
IDA
Genome ProjectT cell receptor complex
GO:0046696
IDA
Genome Projectlipopolysaccharide receptor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001315CARD domain
IPR011029Death-like domain

No MapMan annotations defined for this gene.