Gene: ENSG00000141448 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000141448
Transcript Identifier
ENST00000581694
Gene Type
Coding gene
Location
18 : 22171145-22200823 : positive

Family Information

Homologous gene family
HOM03P002506
(37 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P074165
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
GATA binding protein 6

Identifiers

Type Value
pidENSP00000462313
HGNC4174
UniprotQ92908

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001889
IEA
Genome Projectliver development
GO:0003148
IMP
Genome Projectoutflow tract septum morphogenesis
GO:0003309
IEA
Genome Projecttype B pancreatic cell differentiation
GO:0003310
IEA
Genome Projectpancreatic A cell differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006644
IEA
Genome Projectphospholipid metabolic process
GO:0007493
IEA
Genome Projectendodermal cell fate determination
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008584
IEP
Genome Projectmale gonad development
GO:0010468
IEA
Genome Projectregulation of gene expression
GO:0014898
IEA
Genome Projectcardiac muscle hypertrophy in response to stress
GO:0030855
IEA
Genome Projectepithelial cell differentiation
GO:0031016
IEA
Genome Projectpancreas development
GO:0032911
IMP
Genome Projectnegative regulation of transforming growth factor beta1 production
GO:0032912
IMP
Genome Projectnegative regulation of transforming growth factor beta2 production
GO:0035239
IEA
Genome Projecttube morphogenesis
GO:0035987
IEA
Genome Projectendodermal cell differentiation
GO:0042493
IMP
Genome Projectresponse to drug
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0043627
IEA
Genome Projectresponse to estrogen
GO:0045766
IDA
Genome Projectpositive regulation of angiogenesis
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048645
IEA
Genome Projectorgan formation
GO:0048738
IEA
Genome Projectcardiac muscle tissue development
GO:0051145
IMP
Genome Projectsmooth muscle cell differentiation
GO:0051891
IEA
Genome Projectpositive regulation of cardioblast differentiation
GO:0055007
IEA
Genome Projectcardiac muscle cell differentiation
GO:0060045
IEA
Genome Projectpositive regulation of cardiac muscle cell proliferation
GO:0060430
IEA
Genome Projectlung saccule development
GO:0060486
IEA
Genome ProjectClara cell differentiation
GO:0060510
IEA
Genome ProjectType II pneumocyte differentiation
GO:0060575
IDA
Genome Projectintestinal epithelial cell differentiation
GO:0060947
IMP
Genome Projectcardiac vascular smooth muscle cell differentiation
GO:0070848
IDA
Genome Projectresponse to growth factor
GO:0071158
IDA
Genome Projectpositive regulation of cell cycle arrest
GO:0071371
IEA
Genome Projectcellular response to gonadotropin stimulus
GO:0071456
IDA
Genome Projectcellular response to hypoxia
GO:0071773
IEA
Genome Projectcellular response to BMP stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000979
IEA
Genome ProjectRNA polymerase II core promoter sequence-specific DNA binding
GO:0000981
IMP
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001103
IEA
Genome ProjectRNA polymerase II repressing transcription factor binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005667
IEA
Genome Projecttranscription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000679Zinc finger, GATA-type
IPR008013GATA-type transcription activator, N-terminal
IPR013088Zinc finger, NHR/GATA-type
IPR028437Transcription factor GATA-6

No MapMan annotations defined for this gene.