Gene: ENSG00000141027 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000141027
Transcript Identifier
ENST00000268712
Gene Type
Coding gene
Location
17 : 16032296-16194569 : negative

Family Information

Homologous gene family
HOM03P008869
(9 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P069609
(2 genes in 2 species)
specific family

Descriptions

gene_descr
nuclear receptor corepressor 1

Identifiers

Type Value
pidENSP00000268712
HGNC7672
UniprotO75376
UniprotA0A024RD47

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002361
IEA
Genome ProjectCD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0014067
IEA
Genome Projectnegative regulation of phosphatidylinositol 3-kinase signaling
GO:0021794
IEA
Genome Projectthalamus development
GO:0031065
IEA
Genome Projectpositive regulation of histone deacetylation
GO:0032922
IEA
Genome Projectcircadian regulation of gene expression
GO:0040014
IEA
Genome Projectregulation of multicellular organism growth
GO:0042632
IEA
Genome Projectcholesterol homeostasis
GO:0045892
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0060318
IEA
Genome Projectdefinitive erythrocyte differentiation
GO:0000122
IMP
TAS
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006325
TAS
Genome Projectchromatin organization
GO:0006351
TAS, IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
TAS
Genome Projecttranscription from RNA polymerase II promoter
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0007179
TAS
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007219
TAS
Genome ProjectNotch signaling pathway
GO:0007623
TAS
Genome Projectcircadian rhythm
GO:0010467
TAS
Genome Projectgene expression
GO:0016568
IEA
Genome Projectchromatin modification
GO:0044255
TAS
Genome Projectcellular lipid metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0046329
IDA
Genome Projectnegative regulation of JNK cascade
GO:0051225
IMP
Genome Projectspindle assembly
GO:0072362
IMP
Genome Projectregulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter
GO:0072368
IMP
Genome Projectregulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
GO:2000191
IC
Genome Projectregulation of fatty acid transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003700
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0035033
IEA
Genome Projecthistone deacetylase regulator activity
GO:0042974
IEA
Genome Projectretinoic acid receptor binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0046965
IEA
Genome Projectretinoid X receptor binding
GO:0046966
IBA
IEA
Genome Projectthyroid hormone receptor binding
GO:0001102
IPI
Genome ProjectRNA polymerase II activating transcription factor binding
GO:0003714
IDA, IMP
TAS
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016922
IBA
Genome Projectligand-dependent nuclear receptor binding
GO:0035257
IPI
Genome Projectnuclear hormone receptor binding
GO:0042826
IPI
Genome Projecthistone deacetylase binding
GO:0044212
ISS
Genome Projecttranscription regulatory region DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IC, IEA
Genome Projectnucleus
GO:0005667
IEA
Genome Projecttranscription factor complex
GO:0005737
IEA
Genome Projectcytoplasm
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005876
IDA
Genome Projectspindle microtubule
GO:0016020
IDA
Genome Projectmembrane
GO:0017053
IDA
Genome Projecttranscriptional repressor complex
GO:0000118
IDA
Genome Projecthistone deacetylase complex
GO:0016580
IDA
Genome ProjectSin3 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001005SANT/Myb domain
IPR009057Homeodomain-like
IPR017884SANT domain
IPR031557N-CoR, GPS2-interacting domain

No MapMan annotations defined for this gene.