Gene: ENSG00000140505 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000140505
Transcript Identifier
ENST00000343932
Gene Type
Coding gene
Location
15 : 74749739-74755088 : positive

Family Information

Homologous gene family
HOM03P000006
(1609 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P010226
(8 genes in 5 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
cytochrome P450, family 1, subfamily A, polypeptide 2

Identifiers

Type Value
pidENSP00000342007
HGNC2596
UniprotP05177

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006706
IMP
Genome Projectsteroid catabolic process
GO:0006725
IEA
Genome Projectcellular aromatic compound metabolic process
GO:0006778
IEA
Genome Projectporphyrin-containing compound metabolic process
GO:0006805
TAS
Genome Projectxenobiotic metabolic process
GO:0009403
IDA
Genome Projecttoxin biosynthetic process
GO:0009404
IEA
Genome Projecttoxin metabolic process
GO:0009791
IEA
Genome Projectpost-embryonic development
GO:0009820
IDA
Genome Projectalkaloid metabolic process
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010468
IEA
Genome Projectregulation of gene expression
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0016098
IDA
Genome Projectmonoterpenoid metabolic process
GO:0017144
IDA
Genome Projectdrug metabolic process
GO:0018894
IEA
Genome Projectdibenzo-p-dioxin metabolic process
GO:0019369
TAS
Genome Projectarachidonic acid metabolic process
GO:0019373
TAS
Genome Projectepoxygenase P450 pathway
GO:0030324
IEA
Genome Projectlung development
GO:0032259
TAS
Genome Projectmethylation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032787
IDA
Genome Projectmonocarboxylic acid metabolic process
GO:0035902
IEA
Genome Projectresponse to immobilization stress
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042737
IMP
Genome Projectdrug catabolic process
GO:0042738
IDA
Genome Projectexogenous drug catabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045333
IEA
Genome Projectcellular respiration
GO:0046483
IDA
Genome Projectheterocycle metabolic process
GO:0050665
IEA
Genome Projecthydrogen peroxide biosynthetic process
GO:0055114
IDA
IEA
Genome Projectoxidation-reduction process
GO:0070989
IDA
Genome Projectoxidative demethylation
GO:0071276
IEA
Genome Projectcellular response to cadmium ion
GO:0071615
IDA
Genome Projectoxidative deethylation
GO:0097267
TAS
Genome Projectomega-hydroxylase P450 pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004497
IDA
IEA
Genome Projectmonooxygenase activity
GO:0005506
IEA
Genome Projectiron ion binding
GO:0009055
TAS
Genome Projectelectron carrier activity
GO:0016491
IDA
IEA
Genome Projectoxidoreductase activity
GO:0016705
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712
IMP
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019899
IPI
Genome Projectenzyme binding
GO:0020037
IDA
IEA
Genome Projectheme binding
GO:0032451
IDA
Genome Projectdemethylase activity
GO:0034875
IDA
Genome Projectcaffeine oxidase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070330
IEA
Genome Projectaromatase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
TAS, IEA
Genome Projectendoplasmic reticulum membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0031090
IEA
Genome Projectorganelle membrane
GO:0043231
IDA
IEA
Genome Projectintracellular membrane-bounded organelle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001128Cytochrome P450
IPR002401Cytochrome P450, E-class, group I
IPR008066Cytochrome P450, E-class, group I, CYP1
IPR017972Cytochrome P450, conserved site

No MapMan annotations defined for this gene.