Gene: ENSG00000140465 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000140465
Transcript Identifier
ENST00000567032
Gene Type
Coding gene
Location
15 : 74720489-74723097 : negative

Family Information

Homologous gene family
HOM03P000006
(1609 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P010226
(8 genes in 5 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
cytochrome P450, family 1, subfamily A, polypeptide 1

Identifiers

Type Value
pidENSP00000456585
HGNC2595
UniprotP04798
UniprotA0N0X8

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001889
IEA
Genome Projectliver development
GO:0006778
IEA
Genome Projectporphyrin-containing compound metabolic process
GO:0007568
IEA
Genome Projectaging
GO:0008283
IEA
Genome Projectcell proliferation
GO:0009308
IEA
Genome Projectamine metabolic process
GO:0009404
IEA
Genome Projecttoxin metabolic process
GO:0009611
IEA
Genome Projectresponse to wounding
GO:0009615
IEA
Genome Projectresponse to virus
GO:0009624
IEA
Genome Projectresponse to nematode
GO:0009635
IEA
Genome Projectresponse to herbicide
GO:0009636
IEA
Genome Projectresponse to toxic substance
GO:0009792
IEA
Genome Projectembryo development ending in birth or egg hatching
GO:0009804
IEA
Genome Projectcoumarin metabolic process
GO:0009812
IEA
Genome Projectflavonoid metabolic process
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010041
IEA
Genome Projectresponse to iron(III) ion
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0017143
IEA
Genome Projectinsecticide metabolic process
GO:0018894
IEA
Genome Projectdibenzo-p-dioxin metabolic process
GO:0019341
IEA
Genome Projectdibenzo-p-dioxin catabolic process
GO:0032094
IEA
Genome Projectresponse to food
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032502
IEA
Genome Projectdevelopmental process
GO:0033189
IEA
Genome Projectresponse to vitamin A
GO:0035902
IEA
Genome Projectresponse to immobilization stress
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042904
IEA
Genome Project9-cis-retinoic acid biosynthetic process
GO:0043010
IEA
Genome Projectcamera-type eye development
GO:0046483
IEA
Genome Projectheterocycle metabolic process
GO:0046677
IEA
Genome Projectresponse to antibiotic
GO:0046685
IEA
Genome Projectresponse to arsenic-containing substance
GO:0048565
IEA
Genome Projectdigestive tract development
GO:0050665
IEA
Genome Projecthydrogen peroxide biosynthetic process
GO:0055093
IEA
Genome Projectresponse to hyperoxia
GO:0055114
IDA
IEA
Genome Projectoxidation-reduction process
GO:0060137
IEA
Genome Projectmaternal process involved in parturition
GO:0070365
IEA
Genome Projecthepatocyte differentiation
GO:0070988
IEA
Genome Projectdemethylation
GO:1900087
IEA
Genome Projectpositive regulation of G1/S transition of mitotic cell cycle
GO:0006805
TAS
Genome Projectxenobiotic metabolic process
GO:0017144
IDA
Genome Projectdrug metabolic process
GO:0019369
TAS
Genome Projectarachidonic acid metabolic process
GO:0019373
TAS
Genome Projectepoxygenase P450 pathway
GO:0042359
IC
Genome Projectvitamin D metabolic process
GO:0044255
TAS
Genome Projectcellular lipid metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0071407
IDA
Genome Projectcellular response to organic cyclic compound
GO:0097267
TAS
Genome Projectomega-hydroxylase P450 pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004497
IEA
Genome Projectmonooxygenase activity
GO:0005506
IEA
Genome Projectiron ion binding
GO:0008395
IEA
Genome Projectsteroid hydroxylase activity
GO:0016491
IDA
IEA
Genome Projectoxidoreductase activity
GO:0016679
IEA
Genome Projectoxidoreductase activity, acting on diphenols and related substances as donors
GO:0016705
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016711
IEA
Genome Projectflavonoid 3'-monooxygenase activity
GO:0016712
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019899
IEA
Genome Projectenzyme binding
GO:0020037
IEA
Genome Projectheme binding
GO:0032451
IEA
Genome Projectdemethylase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070330
IEA
Genome Projectaromatase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019825
TAS
Genome Projectoxygen binding
GO:0070576
IDA
Genome Projectvitamin D 24-hydroxylase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
TAS, IEA
Genome Projectendoplasmic reticulum membrane
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0016020
IEA
Genome Projectmembrane
GO:0031090
IEA
Genome Projectorganelle membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001128Cytochrome P450
IPR002401Cytochrome P450, E-class, group I
IPR008066Cytochrome P450, E-class, group I, CYP1
IPR017972Cytochrome P450, conserved site

No MapMan annotations defined for this gene.