Gene: ENSG00000140459 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000140459
Transcript Identifier
ENST00000268053
Gene Type
Coding gene
Location
15 : 74337972-74367585 : negative

Family Information

Homologous gene family
HOM03P000006
(1609 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P004870
(17 genes in 5 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
cytochrome P450, family 11, subfamily A, polypeptide 1

Identifiers

Type Value
pidENSP00000268053
HGNC2590
UniprotP05108

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006082
IEA
Genome Projectorganic acid metabolic process
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006694
IEA
Genome Projectsteroid biosynthetic process
GO:0006700
IDA
TAS, IEA
Genome ProjectC21-steroid hormone biosynthetic process
GO:0006701
IEA
Genome Projectprogesterone biosynthetic process
GO:0006703
IEA
Genome Projectestrogen biosynthetic process
GO:0006805
TAS
Genome Projectxenobiotic metabolic process
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0007617
IEA
Genome Projectmating behavior
GO:0008202
TAS, IEA
Genome Projectsteroid metabolic process
GO:0008203
IDA, IMP
ISS
IEA
Genome Projectcholesterol metabolic process
GO:0008207
IEA
Genome ProjectC21-steroid hormone metabolic process
GO:0008584
IEA
Genome Projectmale gonad development
GO:0009651
IEA
Genome Projectresponse to salt stress
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010212
IEA
Genome Projectresponse to ionizing radiation
GO:0010332
IEA
Genome Projectresponse to gamma radiation
GO:0014037
IEA
Genome ProjectSchwann cell differentiation
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0016125
TAS
Genome Projectsterol metabolic process
GO:0017085
IEA
Genome Projectresponse to insecticide
GO:0018879
IEA
Genome Projectbiphenyl metabolic process
GO:0018894
IEA
Genome Projectdibenzo-p-dioxin metabolic process
GO:0018958
IEA
Genome Projectphenol-containing compound metabolic process
GO:0018963
IEA
Genome Projectphthalate metabolic process
GO:0021549
IEA
Genome Projectcerebellum development
GO:0021766
IEA
Genome Projecthippocampus development
GO:0033197
IEA
Genome Projectresponse to vitamin E
GO:0033327
IEA
Genome ProjectLeydig cell differentiation
GO:0033591
IEA
Genome Projectresponse to L-ascorbic acid
GO:0033595
IEA
Genome Projectresponse to genistein
GO:0034698
IEA
Genome Projectresponse to gonadotropin
GO:0042359
ISS
Genome Projectvitamin D metabolic process
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042542
IEA
Genome Projectresponse to hydrogen peroxide
GO:0043200
IEA
Genome Projectresponse to amino acid
GO:0043279
IEA
Genome Projectresponse to alkaloid
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0043627
IEA
Genome Projectresponse to estrogen
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0044344
IEA
Genome Projectcellular response to fibroblast growth factor stimulus
GO:0046677
IEA
Genome Projectresponse to antibiotic
GO:0046686
IEA
Genome Projectresponse to cadmium ion
GO:0048545
IEA
Genome Projectresponse to steroid hormone
GO:0051412
IEA
Genome Projectresponse to corticosterone
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0060014
IEA
Genome Projectgranulosa cell differentiation
GO:0060135
IEA
Genome Projectmaternal process involved in female pregnancy
GO:0060992
IEA
Genome Projectresponse to fungicide
GO:0061370
IEA
Genome Projecttestosterone biosynthetic process
GO:0071222
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0071236
IEA
Genome Projectcellular response to antibiotic
GO:0071276
IEA
Genome Projectcellular response to cadmium ion
GO:0071320
IEA
Genome Projectcellular response to cAMP
GO:0071347
IEA
Genome Projectcellular response to interleukin-1
GO:0071356
IEA
Genome Projectcellular response to tumor necrosis factor
GO:0071371
IEA
Genome Projectcellular response to gonadotropin stimulus
GO:0071372
IEA
Genome Projectcellular response to follicle-stimulating hormone stimulus
GO:0071375
IEA
Genome Projectcellular response to peptide hormone stimulus
GO:0071560
IEA
Genome Projectcellular response to transforming growth factor beta stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004497
IEA
Genome Projectmonooxygenase activity
GO:0005506
IEA
Genome Projectiron ion binding
GO:0008386
IDA
ISS
TAS, IEA
Genome Projectcholesterol monooxygenase (side-chain-cleaving) activity
GO:0015485
IEA
Genome Projectcholesterol binding
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016705
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037
IDA
IEA
Genome Projectheme binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
ISS
IEA
Genome Projectmitochondrion
GO:0005743
IEA
Genome Projectmitochondrial inner membrane
GO:0005759
TAS
Genome Projectmitochondrial matrix
GO:0016020
IEA
Genome Projectmembrane
GO:0030061
IEA
Genome Projectmitochondrial crista
GO:0031966
IEA
Genome Projectmitochondrial membrane
GO:0043204
IEA
Genome Projectperikaryon

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001128Cytochrome P450
IPR002401Cytochrome P450, E-class, group I
IPR017972Cytochrome P450, conserved site

No MapMan annotations defined for this gene.