Gene: ENSG00000140396 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000140396
Transcript Identifier
ENST00000452400
Gene Type
Coding gene
Location
8 : 70113632-70216745 : negative

Family Information

Homologous gene family
HOM03P012843
(6 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P030826
(3 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
nuclear receptor coactivator 2

Identifiers

Type Value
pidENSP00000399968
HGNC7669
UniprotQ15596

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006325
TAS
Genome Projectchromatin organization
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
NAS, IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007623
IEA
Genome Projectcircadian rhythm
GO:0008206
TAS
Genome Projectbile acid metabolic process
GO:0010906
IEA
Genome Projectregulation of glucose metabolic process
GO:0015721
TAS
Genome Projectbile acid and bile salt transport
GO:0016573
IEA
Genome Projecthistone acetylation
GO:0032870
IBA
Genome Projectcellular response to hormone stimulus
GO:0032922
ISS
IEA
Genome Projectcircadian regulation of gene expression
GO:0044255
TAS
Genome Projectcellular lipid metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045475
IEA
Genome Projectlocomotor rhythm
GO:0045892
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045944
IBA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048511
IEA
Genome Projectrhythmic process
GO:2000273
IEA
Genome Projectpositive regulation of receptor activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003713
ISS
NAS, IEA
Genome Projecttranscription coactivator activity
GO:0004402
IEA
Genome Projecthistone acetyltransferase activity
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IEA
Genome Projecttranscription factor binding
GO:0016922
IPI
Genome Projectligand-dependent nuclear receptor binding
GO:0030374
IDA
IEA
Genome Projectligand-dependent nuclear receptor transcription coactivator activity
GO:0030375
IEA
Genome Projectthyroid hormone receptor coactivator activity
GO:0035257
IPI
IEA
Genome Projectnuclear hormone receptor binding
GO:0046983
IEA
Genome Projectprotein dimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IBA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000014PAS domain
IPR001610PAC motif
IPR008955Nuclear receptor coactivator Src-1
IPR009110Nuclear receptor coactivator, interlocking
IPR010011Domain of unknown function DUF1518
IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
IPR013767PAS fold
IPR014920Nuclear receptor coactivator, Ncoa-type, interlocking
IPR014935Steroid receptor coactivator
IPR017426Nuclear receptor coactivator
IPR028822Nuclear receptor coactivator 2
IPR032565Domain of unknown function DUF4927

No MapMan annotations defined for this gene.