Gene: ENSG00000139193 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000139193
Transcript Identifier
ENST00000266557
Gene Type
Coding gene
Location
12 : 6445096-6451392 : positive

Family Information

Homologous gene family
HOM03P034737
(2 genes in 2 species)
specific family

Descriptions

gene_descr
CD27 molecule

Identifiers

Type Value
pidENSP00000266557
HGNC11922
UniprotP26842

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007166
NAS
Genome Projectcell surface receptor signaling pathway
GO:0008588
NAS
Genome Projectrelease of cytoplasmic sequestered NF-kappaB
GO:0016064
NAS
Genome Projectimmunoglobulin mediated immune response
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0043154
IDA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045579
NAS
Genome Projectpositive regulation of B cell differentiation
GO:0046330
ISS
IEA
Genome Projectpositive regulation of JNK cascade
GO:0070233
IEA
Genome Projectnegative regulation of T cell apoptotic process
GO:0097191
IDA
Genome Projectextrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004888
NAS
Genome Projecttransmembrane signaling receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0043027
IDA
Genome Projectcysteine-type endopeptidase inhibitor activity involved in apoptotic process

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
NAS
Genome Projectextracellular region
GO:0005622
NAS
Genome Projectintracellular
GO:0005887
NAS
Genome Projectintegral component of plasma membrane
GO:0009897
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001368TNFR/NGFR cysteine-rich region
IPR022328Tumour necrosis factor receptor 7

No MapMan annotations defined for this gene.