Gene: ENSG00000138792 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000138792
Transcript Identifier
ENST00000265162
Gene Type
Coding gene
Location
4 : 110476415-110561558 : positive

Family Information

Homologous gene family
HOM03P000430
(106 genes in 31 species)
specific family
Orthologous gene family
ORTHO03P012021
(7 genes in 4 species)
specific family

Descriptions

gene_descr
glutamyl aminopeptidase (aminopeptidase A)

Identifiers

Type Value
pidENSP00000265162
HGNC3355
UniprotQ07075

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
ISS
IEA
Genome Projectangiogenesis
GO:0002003
TAS
Genome Projectangiotensin maturation
GO:0002005
NAS
Genome Projectangiotensin catabolic process in blood
GO:0003081
IDA
NAS
Genome Projectregulation of systemic arterial blood pressure by renin-angiotensin
GO:0006508
IBA
IEA
Genome Projectproteolysis
GO:0007267
NAS
Genome Projectcell-cell signaling
GO:0008283
IDA
NAS
Genome Projectcell proliferation
GO:0016477
IDA
Genome Projectcell migration
GO:0032835
ISS
IEA
Genome Projectglomerulus development
GO:0043171
IBA
Genome Projectpeptide catabolic process
GO:0044267
TAS
Genome Projectcellular protein metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004177
IDA
IEA
Genome Projectaminopeptidase activity
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0008237
EXP
IEA
Genome Projectmetallopeptidase activity
GO:0008270
IBA
IEA
Genome Projectzinc ion binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0042277
IBA
Genome Projectpeptide binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070006
IDA
NAS
Genome Projectmetalloaminopeptidase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005765
IDA
Genome Projectlysosomal membrane
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005887
NAS
Genome Projectintegral component of plasma membrane
GO:0005903
ISS
IEA
Genome Projectbrush border
GO:0009897
ISS
IEA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016324
ISS
IEA
Genome Projectapical plasma membrane
GO:0031410
ISS
IEA
Genome Projectcytoplasmic vesicle
GO:0045177
ISS
IEA
Genome Projectapical part of cell
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001930Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
IPR014782Peptidase M1, membrane alanine aminopeptidase, N-terminal
IPR024571ERAP1-like C-terminal domain

No MapMan annotations defined for this gene.