Gene: ENSG00000136943 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000136943
Transcript Identifier
ENST00000259470
Gene Type
Coding gene
Location
9 : 97032949-97038043 : negative

Family Information

Homologous gene family
HOM03P000044
(550 genes in 34 species)
specific family
Orthologous gene family
ORTHO03P000333
(54 genes in 32 species)
specific family

Descriptions

gene_descr
cathepsin V

Identifiers

Type Value
pidENSP00000259470
HGNC2538
UniprotO60911
UniprotA0A024R141

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006508
IEA
Genome Projectproteolysis
GO:0007154
IEA
Genome Projectcell communication
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0008584
IEA
Genome Projectmale gonad development
GO:0009267
IEA
Genome Projectcellular response to starvation
GO:0009749
IEA
Genome Projectresponse to glucose
GO:0010259
IEA
Genome Projectmulticellular organismal aging
GO:0010839
IEA
Genome Projectnegative regulation of keratinocyte proliferation
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0016485
IEA
Genome Projectprotein processing
GO:0016540
IEA
Genome Projectprotein autoprocessing
GO:0021675
IEA
Genome Projectnerve development
GO:0031069
IEA
Genome Projecthair follicle morphogenesis
GO:0034698
IEA
Genome Projectresponse to gonadotropin
GO:0046697
IEA
Genome Projectdecidualization
GO:0048102
IEA
Genome Projectautophagic cell death
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0060008
IEA
Genome ProjectSertoli cell differentiation
GO:2000249
IEA
Genome Projectregulation of actin cytoskeleton reorganization
GO:0019886
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0022617
TAS
Genome Projectextracellular matrix disassembly
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0051603
IBA
Genome Projectproteolysis involved in cellular protein catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004177
IEA
Genome Projectaminopeptidase activity
GO:0004197
TAS, IEA
Genome Projectcysteine-type endopeptidase activity
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0008234
TAS, IEA
Genome Projectcysteine-type peptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016807
IEA
Genome Projectcysteine-type carboxypeptidase activity
GO:0030984
IEA
Genome Projectkininogen binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0042277
IEA
Genome Projectpeptide binding
GO:0042393
IEA
Genome Projecthistone binding
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IBA
IEA
Genome Projectextracellular space
GO:0005634
IEA
Genome Projectnucleus
GO:0005730
IEA
Genome Projectnucleolus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005764
IBA
IEA
Genome Projectlysosome
GO:0005773
IEA
Genome Projectvacuole
GO:0005902
IEA
Genome Projectmicrovillus
GO:0009897
IEA
Genome Projectexternal side of plasma membrane
GO:0030141
IEA
Genome Projectsecretory granule
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0043005
IEA
Genome Projectneuron projection
GO:0043204
IEA
Genome Projectperikaryon
GO:0045177
IEA
Genome Projectapical part of cell
GO:0005576
TAS
Genome Projectextracellular region
GO:0043202
TAS
Genome Projectlysosomal lumen
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000169Cysteine peptidase, cysteine active site
IPR000668Peptidase C1A, papain C-terminal
IPR013128Peptidase C1A
IPR013201Cathepsin propeptide inhibitor domain (I29)
IPR025660Cysteine peptidase, histidine active site
IPR025661Cysteine peptidase, asparagine active site

No MapMan annotations defined for this gene.