Gene: ENSG00000136826 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000136826
Transcript Identifier
ENST00000374672
Gene Type
Coding gene
Location
9 : 107485751-107489172 : negative

Family Information

Homologous gene family
HOM03P000007
(1601 genes in 28 species)
specific family
Orthologous gene family
ORTHO03P068098
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
Kruppel-like factor 4 (gut)

Identifiers

Type Value
pidENSP00000363804
HGNC6348
UniprotO43474

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
ISS
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007500
TAS
Genome Projectmesodermal cell fate determination
GO:0008285
TAS, IEA
Genome Projectnegative regulation of cell proliferation
GO:0009913
IEA
Genome Projectepidermal cell differentiation
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0014067
IEA
Genome Projectnegative regulation of phosphatidylinositol 3-kinase signaling
GO:0014740
IEA
Genome Projectnegative regulation of muscle hyperplasia
GO:0019827
ISS
IEA
Genome Projectstem cell population maintenance
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030336
IEA
Genome Projectnegative regulation of cell migration
GO:0031077
IEA
Genome Projectpost-embryonic camera-type eye development
GO:0032088
IDA
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0032270
IMP
Genome Projectpositive regulation of cellular protein metabolic process
GO:0032526
IEA
Genome Projectresponse to retinoic acid
GO:0034115
IDA
Genome Projectnegative regulation of heterotypic cell-cell adhesion
GO:0035019
TAS
Genome Projectsomatic stem cell population maintenance
GO:0035166
IMP
Genome Projectpost-embryonic hemopoiesis
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0043154
IDA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043551
IEA
Genome Projectregulation of phosphatidylinositol 3-kinase activity
GO:0045415
IDA
Genome Projectnegative regulation of interleukin-8 biosynthetic process
GO:0045429
IMP
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0045444
ISS
IEA
Genome Projectfat cell differentiation
GO:0045595
ISS
IEA
Genome Projectregulation of cell differentiation
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
ISS
NAS, IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IMP, IGI
ISS
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046985
IMP
Genome Projectpositive regulation of hemoglobin biosynthetic process
GO:0048662
IEA
Genome Projectnegative regulation of smooth muscle cell proliferation
GO:0048730
IEA
Genome Projectepidermis morphogenesis
GO:0050728
TAS
Genome Projectnegative regulation of inflammatory response
GO:0051247
IGI
Genome Projectpositive regulation of protein metabolic process
GO:0051898
IEA
Genome Projectnegative regulation of protein kinase B signaling
GO:0051973
IDA
Genome Projectpositive regulation of telomerase activity
GO:0060070
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0060761
IDA
Genome Projectnegative regulation of response to cytokine stimulus
GO:0070301
IEA
Genome Projectcellular response to hydrogen peroxide
GO:0070373
IEA
Genome Projectnegative regulation of ERK1 and ERK2 cascade
GO:0071300
IEA
Genome Projectcellular response to retinoic acid
GO:0071363
IDA
Genome Projectcellular response to growth factor stimulus
GO:0071407
IEA
Genome Projectcellular response to organic cyclic compound
GO:0071409
IEA
Genome Projectcellular response to cycloheximide
GO:0071499
IMP
Genome Projectcellular response to laminar fluid shear stress
GO:0090051
IDA
Genome Projectnegative regulation of cell migration involved in sprouting angiogenesis
GO:1901653
IEA
Genome Projectcellular response to peptide
GO:2000342
IDA
Genome Projectnegative regulation of chemokine (C-X-C motif) ligand 2 production

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000987
IDA
Genome Projectcore promoter proximal region sequence-specific DNA binding
GO:0001010
ISS
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding transcription factor recruiting
GO:0001047
IEA
Genome Projectcore promoter binding
GO:0001077
IMP
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085
IPI
ISS
Genome ProjectRNA polymerase II transcription factor binding
GO:0001190
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription factor binding
GO:0001221
IEA
Genome Projecttranscription cofactor binding
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003690
IEA
Genome Projectdouble-stranded DNA binding
GO:0003700
TAS, NAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008013
IEA
Genome Projectbeta-catenin binding
GO:0008134
IEA
Genome Projecttranscription factor binding
GO:0008270
NAS
Genome Projectzinc ion binding
GO:0035014
IEA
Genome Projectphosphatidylinositol 3-kinase regulator activity
GO:0042826
IEA
Genome Projecthistone deacetylase binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
ISS
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000785
IEA
Genome Projectchromatin
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005667
IEA
Genome Projecttranscription factor complex
GO:0005719
IEA
Genome Projectnuclear euchromatin
GO:0044798
IEA
Genome Projectnuclear transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007087Zinc finger, C2H2
IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
IPR015880Zinc finger, C2H2-like

No MapMan annotations defined for this gene.