Gene: ENSG00000136381 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000136381
Transcript Identifier
ENST00000258886
Gene Type
Coding gene
Location
15 : 78438338-78498143 : positive

Family Information

Homologous gene family
HOM03P003729
(26 genes in 10 species)
specific family

Descriptions

gene_descr
iron-responsive element binding protein 2

Identifiers

Type Value
pidENSP00000258886
HGNC6115
UniprotA0A0A6YY96

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006417
IEA
Genome Projectregulation of translation
GO:0006782
IEA
Genome Projectprotoporphyrinogen IX biosynthetic process
GO:0006826
IEA
Genome Projectiron ion transport
GO:0006879
IEA
Genome Projectcellular iron ion homeostasis
GO:0008152
IEA
Genome Projectmetabolic process
GO:0009791
IEA
Genome Projectpost-embryonic development
GO:0010468
IEA
Genome Projectregulation of gene expression
GO:0017148
IEA
Genome Projectnegative regulation of translation
GO:0030316
IEA
Genome Projectosteoclast differentiation
GO:0034101
IEA
Genome Projecterythrocyte homeostasis
GO:0050892
IEA
Genome Projectintestinal absorption
GO:0055072
IEA
Genome Projectiron ion homeostasis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030350
IEA
Genome Projectiron-responsive element binding
GO:0030371
IEA
Genome Projecttranslation repressor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005829
IEA
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000573Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
IPR001030Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
IPR006249Aconitase/Iron-responsive element-binding protein 2
IPR015928Aconitase/3-isopropylmalate dehydratase, swivel
IPR015931Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
IPR015932Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2
IPR015937Aconitase/isopropylmalate dehydratase
IPR018136Aconitase family, 4Fe-4S cluster binding site
IPR029755Iron regulatory protein 2

No MapMan annotations defined for this gene.