Gene: ENSG00000136160 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000136160
Transcript Identifier
ENST00000377211
Gene Type
Coding gene
Location
13 : 77898200-77919615 : negative

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P067319
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
endothelin receptor type B

Identifiers

Type Value
pidENSP00000366416
HGNC3180
UniprotP24530
UniprotA0A024R638

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001755
IEA
Genome Projectneural crest cell migration
GO:0001934
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0006885
IEA
Genome Projectregulation of pH
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007200
TAS, IEA
Genome Projectphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007422
IEA
Genome Projectperipheral nervous system development
GO:0007497
IEA
Genome Projectposterior midgut development
GO:0007568
IEA
Genome Projectaging
GO:0008217
IEA
Genome Projectregulation of blood pressure
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0014043
ISS
IEA
Genome Projectnegative regulation of neuron maturation
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0019233
IEA
Genome Projectsensory perception of pain
GO:0019934
IEA
Genome ProjectcGMP-mediated signaling
GO:0030318
IEA
Genome Projectmelanocyte differentiation
GO:0031620
IEA
Genome Projectregulation of fever generation
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0035645
ISS
IEA
Genome Projectenteric smooth muscle cell differentiation
GO:0035810
IEA
Genome Projectpositive regulation of urine volume
GO:0035815
IEA
Genome Projectpositive regulation of renal sodium excretion
GO:0042045
IEA
Genome Projectepithelial fluid transport
GO:0042310
IMP
IEA
Genome Projectvasoconstriction
GO:0042311
IEA
Genome Projectvasodilation
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043473
IEA
Genome Projectpigmentation
GO:0048066
IEA
Genome Projectdevelopmental pigmentation
GO:0048265
IEA
Genome Projectresponse to pain
GO:0048484
ISS
IEA
Genome Projectenteric nervous system development
GO:0050678
IEA
Genome Projectregulation of epithelial cell proliferation
GO:0051930
IEA
Genome Projectregulation of sensory perception of pain
GO:0060406
IEA
Genome Projectpositive regulation of penile erection
GO:0071222
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0086100
IDA, IMP
IEA
Genome Projectendothelin receptor signaling pathway
GO:0000122
IMP
ISS
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0007166
TAS
Genome Projectcell surface receptor signaling pathway
GO:0007194
TAS
Genome Projectnegative regulation of adenylate cyclase activity
GO:0007399
TAS
Genome Projectnervous system development
GO:0014826
IMP
Genome Projectvein smooth muscle contraction
GO:0032269
IMP
Genome Projectnegative regulation of cellular protein metabolic process
GO:0048246
IMP
Genome Projectmacrophage chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004962
IDA, IMP
IEA
Genome Projectendothelin receptor activity
GO:0031702
IEA
Genome Projecttype 1 angiotensin receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0017046
IPI
Genome Projectpeptide hormone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031965
IEA
Genome Projectnuclear membrane
GO:0045121
IEA
Genome Projectmembrane raft
GO:0005887
TAS
Genome Projectintegral component of plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000499Endothelin receptor family
IPR001112Endothelin receptor B
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.