Gene: ENSG00000135503 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000135503
Transcript Identifier
ENST00000541224
Gene Type
Coding gene
Location
12 : 51951744-51994110 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P010260
(8 genes in 4 species)
specific family

Descriptions

gene_descr
activin A receptor, type IB

Identifiers

Type Value
pidENSP00000442656
HGNC172
UniprotP36896

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000082
IDA
Genome ProjectG1/S transition of mitotic cell cycle
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001942
IEA
Genome Projecthair follicle development
GO:0006355
IDA
Genome Projectregulation of transcription, DNA-templated
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0007165
IDA
Genome Projectsignal transduction
GO:0007178
TAS, IEA
Genome Projecttransmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007417
IEA
Genome Projectcentral nervous system development
GO:0009966
IEA
Genome Projectregulation of signal transduction
GO:0010628
IEA
Genome Projectpositive regulation of gene expression
GO:0010629
IEA
Genome Projectnegative regulation of gene expression
GO:0010862
IEA
Genome Projectpositive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018107
IDA
Genome Projectpeptidyl-threonine phosphorylation
GO:0023014
IEA
Genome Projectsignal transduction by protein phosphorylation
GO:0030308
IDA
Genome Projectnegative regulation of cell growth
GO:0032924
IDA, IMP
Genome Projectactivin receptor signaling pathway
GO:0032927
IDA
Genome Projectpositive regulation of activin receptor signaling pathway
GO:0038092
IGI
Genome Projectnodal signaling pathway
GO:0045648
IDA
Genome Projectpositive regulation of erythrocyte differentiation
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046545
IEA
Genome Projectdevelopment of primary female sexual characteristics
GO:0046777
IDA
Genome Projectprotein autophosphorylation
GO:0097191
IMP
Genome Projectextrinsic apoptotic signaling pathway
GO:1901165
IDA
Genome Projectpositive regulation of trophoblast cell migration

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
EXP, IDA
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004675
NAS, IEA
Genome Projecttransmembrane receptor protein serine/threonine kinase activity
GO:0004702
IEA
Genome Projectreceptor signaling protein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IDA
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016361
IDA
TAS
Genome Projectactivin receptor activity, type I
GO:0016740
IEA
Genome Projecttransferase activity
GO:0031625
NAS
Genome Projectubiquitin protein ligase binding
GO:0034711
IPI
Genome Projectinhibin binding
GO:0046332
IDA
IEA
Genome ProjectSMAD binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0048185
IDA
IEA
Genome Projectactivin binding
GO:0017002
IDA
Genome Projectactivin-activated receptor activity
GO:0019838
IPI
Genome Projectgrowth factor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IDA
Genome Projectintegral component of plasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0043235
IDA
Genome Projectreceptor complex
GO:0048179
IDA
Genome Projectactivin receptor complex
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000333Ser/Thr protein kinase, TGFB receptor
IPR000472Activin types I and II receptor domain
IPR000719Protein kinase domain
IPR003605GS domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.