Gene: ENSG00000135312 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000135312
Transcript Identifier
ENST00000369947
Gene Type
Coding gene
Location
6 : 77462231-77463403 : negative

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P072879
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Identifiers

Type Value
pidENSP00000358963
HGNC5287
UniprotP28222
UniprotX5D7I5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002031
IEA
Genome ProjectG-protein coupled receptor internalization
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007187
TAS
Genome ProjectG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007198
IDA
Genome Projectadenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007205
IEA
Genome Projectprotein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007268
TAS, IEA
Genome Projectsynaptic transmission
GO:0007610
IEA
Genome Projectbehavior
GO:0007631
IEA
Genome Projectfeeding behavior
GO:0014059
IEA
Genome Projectregulation of dopamine secretion
GO:0014063
ISS
IEA
Genome Projectnegative regulation of serotonin secretion
GO:0030818
IDA
Genome Projectnegative regulation of cAMP biosynthetic process
GO:0032229
IEA
Genome Projectnegative regulation of synaptic transmission, GABAergic
GO:0035690
IDA
Genome Projectcellular response to drug
GO:0042220
IEA
Genome Projectresponse to cocaine
GO:0042310
IEA
Genome Projectvasoconstriction
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042756
IEA
Genome Projectdrinking behavior
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0046849
IEA
Genome Projectbone remodeling
GO:0050795
IEA
Genome Projectregulation of behavior
GO:0051385
IEA
Genome Projectresponse to mineralocorticoid
GO:0051967
IEA
Genome Projectnegative regulation of synaptic transmission, glutamatergic
GO:0071312
IDA
Genome Projectcellular response to alkaloid
GO:0071502
IEA
Genome Projectcellular response to temperature stimulus
GO:0007210
IEA
Genome Projectserotonin receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004993
IDA
IEA
Genome Projectserotonin receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008144
IEA
Genome Projectdrug binding
GO:0051378
IEA
Genome Projectserotonin binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IMP
TAS, IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR0021475-Hydroxytryptamine 1B receptor
IPR0022315-hydroxytryptamine receptor family
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.