Gene: ENSG00000135111 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000135111
Transcript Identifier
ENST00000257566
Gene Type
Coding gene
Location
12 : 114671841-114683200 : negative

Family Information

Homologous gene family
HOM03P001268
(54 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P024319
(4 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
T-box 3

Identifiers

Type Value
pidENSP00000257566
HGNC11602
UniprotO15119
UniprotA0A024RBL6

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001568
IEA
Genome Projectblood vessel development
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001947
IEA
Genome Projectheart looping
GO:0003007
IEA
Genome Projectheart morphogenesis
GO:0003151
IEA
Genome Projectoutflow tract morphogenesis
GO:0003167
IEA
Genome Projectatrioventricular bundle cell differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0010159
IEA
Genome Projectspecification of organ position
GO:0019827
IEA
Genome Projectstem cell population maintenance
GO:0021761
IEA
Genome Projectlimbic system development
GO:0030857
IEA
Genome Projectnegative regulation of epithelial cell differentiation
GO:0035050
IEA
Genome Projectembryonic heart tube development
GO:0035108
IEA
Genome Projectlimb morphogenesis
GO:0035116
IEA
Genome Projectembryonic hindlimb morphogenesis
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0055007
IEA
Genome Projectcardiac muscle cell differentiation
GO:0060021
IEA
Genome Projectpalate development
GO:0060412
IEA
Genome Projectventricular septum morphogenesis
GO:0060444
IEA
Genome Projectbranching involved in mammary gland duct morphogenesis
GO:0060596
IEA
Genome Projectmammary placode formation
GO:0060923
IEA
Genome Projectcardiac muscle cell fate commitment
GO:0060931
IEA
Genome Projectsinoatrial node cell development
GO:2000648
IEA
Genome Projectpositive regulation of stem cell proliferation
GO:0001501
IMP
Genome Projectskeletal system development
GO:0006357
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007569
IDA
Genome Projectcell aging
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0008595
IMP
Genome Projectanterior/posterior axis specification, embryo
GO:0009887
IDA
Genome Projectorgan morphogenesis
GO:0030539
IMP
Genome Projectmale genitalia development
GO:0030540
IMP
Genome Projectfemale genitalia development
GO:0030879
IMP
Genome Projectmammary gland development
GO:0032275
IMP
Genome Projectluteinizing hormone secretion
GO:0035115
IMP
Genome Projectembryonic forelimb morphogenesis
GO:0035136
IDA
Genome Projectforelimb morphogenesis
GO:0042733
IMP
Genome Projectembryonic digit morphogenesis
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0045662
IDA
Genome Projectnegative regulation of myoblast differentiation
GO:0045787
IDA
Genome Projectpositive regulation of cell cycle
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0046884
IMP
Genome Projectfollicle-stimulating hormone secretion
GO:0048332
IMP
Genome Projectmesoderm morphogenesis
GO:0090398
IDA
Genome Projectcellular senescence

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001085
ISS
IEA
Genome ProjectRNA polymerase II transcription factor binding
GO:0001102
ISS
IEA
Genome ProjectRNA polymerase II activating transcription factor binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003700
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078
IDA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
IDA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001699Transcription factor, T-box
IPR008967p53-like transcription factor, DNA-binding
IPR018186Transcription factor, T-box, conserved site
IPR022582Transcription factor, T-box, region of unknown function

No MapMan annotations defined for this gene.