Gene: ENSG00000135018 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000135018
Transcript Identifier
ENST00000376395
Gene Type
Coding gene
Location
9 : 83661787-83707679 : negative

Family Information

Homologous gene family
HOM03P001058
(60 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000750
(44 genes in 37 species)
specific family

Descriptions

gene_descr
ubiquilin 1

Identifiers

Type Value
pidENSP00000365576
HGNC12508
UniprotQ9UMX0
UniprotA0A024R284

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031396
IDA
IEA
Genome Projectregulation of protein ubiquitination
GO:0034140
IEA
Genome Projectnegative regulation of toll-like receptor 3 signaling pathway
GO:0006914
IEA
Genome Projectautophagy
GO:0016241
IMP
Genome Projectregulation of macroautophagy
GO:0030433
IMP
Genome ProjectER-associated ubiquitin-dependent protein catabolic process
GO:0031398
IDA
Genome Projectpositive regulation of protein ubiquitination
GO:0034976
IMP
Genome Projectresponse to endoplasmic reticulum stress
GO:0035973
IDA
Genome Projectaggrephagy
GO:0071456
IMP
Genome Projectcellular response to hypoxia
GO:1901097
IMP
Genome Projectnegative regulation of autophagosome maturation
GO:1901340
IMP
Genome Projectnegative regulation of store-operated calcium channel activity
GO:1902175
IMP
Genome Projectregulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1903071
IMP
Genome Projectpositive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785
IMP
Genome Projectregulation of autophagosome assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0019900
IPI
Genome Projectkinase binding
GO:0031593
IDA
Genome Projectpolyubiquitin binding
GO:0042802
IPI
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005776
IDA
IEA
Genome Projectautophagosome
GO:0000502
IEA
Genome Projectproteasome complex
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
IDA, IMP
IEA
Genome Projectcytoplasm
GO:0005783
IDA
IEA
Genome Projectendoplasmic reticulum
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016235
IDA
Genome Projectaggresome
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0043234
IDA
Genome Projectprotein complex
GO:0048471
IDA
NAS
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000626Ubiquitin domain
IPR006636Heat shock chaperonin-binding
IPR009060UBA-like
IPR015496Ubiquilin
IPR015940Ubiquitin-associated domain
IPR028430Ubiquilin-1/2
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.