Gene: ENSG00000134640 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000134640
Transcript Identifier
ENST00000257068
Gene Type
Coding gene
Location
11 : 92969726-92982312 : positive

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P074604
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
melatonin receptor 1B

Identifiers

Type Value
pidENSP00000257068
HGNC7464
UniprotP49286

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007187
TAS
Genome ProjectG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0007623
IBA
Genome Projectcircadian rhythm
GO:0030824
IEA
Genome Projectnegative regulation of cGMP metabolic process
GO:0042593
IMP
Genome Projectglucose homeostasis
GO:0042753
IEA
Genome Projectpositive regulation of circadian rhythm
GO:0043010
IEA
Genome Projectcamera-type eye development
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045909
IEA
Genome Projectpositive regulation of vasodilation
GO:0046010
IEA
Genome Projectpositive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046676
IEA
Genome Projectnegative regulation of insulin secretion
GO:0050796
IMP
Genome Projectregulation of insulin secretion
GO:0051481
IEA
Genome Projectnegative regulation of cytosolic calcium ion concentration
GO:0051970
IEA
Genome Projectnegative regulation of transmission of nerve impulse
GO:0051971
IEA
Genome Projectpositive regulation of transmission of nerve impulse
GO:0098908
IEA
Genome Projectregulation of neuronal action potential
GO:1902260
IEA
Genome Projectnegative regulation of delayed rectifier potassium channel activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
TAS, IEA
Genome ProjectG-protein coupled receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008502
TAS, IEA
Genome Projectmelatonin receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000025Melatonin receptor family
IPR000276G protein-coupled receptor, rhodopsin-like
IPR002278Melatonin receptor 1A
IPR017452GPCR, rhodopsin-like, 7TM
IPR027459Melatonin receptor 1B

No MapMan annotations defined for this gene.