Gene: ENSG00000134489 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000134489
Transcript Identifier
ENST00000256906
Gene Type
Coding gene
Location
18 : 24460729-24477562 : positive

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P064917
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
histamine receptor H4

Identifiers

Type Value
pidENSP00000256906
HGNC17383
UniprotQ9H3N8

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006954
IBA
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007194
IBA
Genome Projectnegative regulation of adenylate cyclase activity
GO:0007204
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0008150
ND
Genome Projectbiological_process
GO:0043408
IEA
Genome Projectregulation of MAPK cascade
GO:0010579
IBA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004969
IBA
NAS, IEA
Genome Projecthistamine receptor activity
GO:0051381
IBA
Genome Projecthistamine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IBA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR008102Histamine H4 receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.