Gene: ENSG00000133703 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000133703
Transcript Identifier
ENST00000256078
Gene Type
Coding gene
Location
12 : 25215441-25245384 : negative

Family Information

Homologous gene family
HOM03P000013
(1389 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P006348
(13 genes in 9 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
Kirsten rat sarcoma viral oncogene homolog

Identifiers

Type Value
pidENSP00000256078
HGNC6407
UniprotP01116
UniprotL7RSL8

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007264
TAS, IEA
Genome Projectsmall GTPase mediated signal transduction
GO:0008542
IEA
Genome Projectvisual learning
GO:0019221
IEA
Genome Projectcytokine-mediated signaling pathway
GO:0030036
IEA
Genome Projectactin cytoskeleton organization
GO:0032228
IEA
Genome Projectregulation of synaptic transmission, GABAergic
GO:0035022
IEA
Genome Projectpositive regulation of Rac protein signal transduction
GO:0035176
IEA
Genome Projectsocial behavior
GO:0038002
IEA
Genome Projectendocrine signaling
GO:0043406
IEA
Genome Projectpositive regulation of MAP kinase activity
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045596
IEA
Genome Projectnegative regulation of cell differentiation
GO:0048169
IEA
Genome Projectregulation of long-term neuronal synaptic plasticity
GO:0048873
IEA
Genome Projecthomeostasis of number of cells within a tissue
GO:0051000
IEA
Genome Projectpositive regulation of nitric-oxide synthase activity
GO:0051092
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051146
IEA
Genome Projectstriated muscle cell differentiation
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0051385
IEA
Genome Projectresponse to mineralocorticoid
GO:0060441
IEA
Genome Projectepithelial tube branching involved in lung morphogenesis
GO:0000165
TAS
Genome ProjectMAPK cascade
GO:0000186
TAS
Genome Projectactivation of MAPKK activity
GO:0001934
IMP
Genome Projectpositive regulation of protein phosphorylation
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007265
TAS
Genome ProjectRas protein signal transduction
GO:0007411
TAS
Genome Projectaxon guidance
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008284
IMP
Genome Projectpositive regulation of cell proliferation
GO:0008286
TAS
Genome Projectinsulin receptor signaling pathway
GO:0008543
TAS
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0010628
IMP
Genome Projectpositive regulation of gene expression
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048010
TAS
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0050900
TAS
Genome Projectleukocyte migration

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0005525
IEA
Genome ProjectGTP binding
GO:0019002
IEA
Genome ProjectGMP binding
GO:0019003
IEA
Genome ProjectGDP binding
GO:0030275
IEA
Genome ProjectLRR domain binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0032403
IDA
Genome Projectprotein complex binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IEA
Genome Projectmitochondrion
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0045121
IEA
Genome Projectmembrane raft
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0031234
IDA
Genome Projectextrinsic component of cytoplasmic side of plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001806Small GTPase superfamily
IPR005225Small GTP-binding protein domain
IPR020849Small GTPase superfamily, Ras type
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.