Gene: ENSG00000133661 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000133661
Transcript Identifier
ENST00000372292
Gene Type
Coding gene
Location
10 : 79937852-79946659 : negative

Family Information

Homologous gene family
HOM03P000086
(312 genes in 10 species)
specific family
Orthologous gene family
ORTHO03P071177
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
surfactant protein D

Identifiers

Type Value
pidENSP00000361366
HGNC10803
UniprotP35247

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001817
NAS
Genome Projectregulation of cytokine production
GO:0002376
IEA
Genome Projectimmune system process
GO:0006898
TAS
Genome Projectreceptor-mediated endocytosis
GO:0007585
IEA
Genome Projectrespiratory gaseous exchange
GO:0042130
TAS
Genome Projectnegative regulation of T cell proliferation
GO:0042742
TAS
Genome Projectdefense response to bacterium
GO:0043129
IMP
Genome Projectsurfactant homeostasis
GO:0045085
TAS
Genome Projectnegative regulation of interleukin-2 biosynthetic process
GO:0045087
TAS, IEA
Genome Projectinnate immune response
GO:0048246
TAS
Genome Projectmacrophage chemotaxis
GO:0048286
IMP
Genome Projectlung alveolus development
GO:0050766
TAS
Genome Projectpositive regulation of phagocytosis
GO:0072593
TAS
Genome Projectreactive oxygen species metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0030246
TAS, IEA
Genome Projectcarbohydrate binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005578
IEA
Genome Projectproteinaceous extracellular matrix
GO:0005581
IEA
Genome Projectcollagen trimer
GO:0005615
IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005764
TAS
Genome Projectlysosome
GO:0030139
TAS
Genome Projectendocytic vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001304C-type lectin
IPR008160Collagen triple helix repeat
IPR015097Lung surfactant protein D coiled-coil trimerisation
IPR016186C-type lectin-like
IPR016187C-type lectin fold
IPR018378C-type lectin, conserved site

No MapMan annotations defined for this gene.