Gene: ENSG00000133124 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000133124
Transcript Identifier
ENST00000372129
Gene Type
Coding gene
Location
X : 108732571-108736344 : negative

Family Information

Homologous gene family
HOM03P009147
(9 genes in 3 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
insulin receptor substrate 4

Identifiers

Type Value
pidENSP00000361202
HGNC6128
UniprotO14654

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
TAS, IEA
Genome Projectsignal transduction
GO:0008286
IBA
Genome Projectinsulin receptor signaling pathway
GO:0009967
TAS
Genome Projectpositive regulation of signal transduction
GO:0019216
IBA
Genome Projectregulation of lipid metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
TAS, IEA
Genome Projectsignal transducer activity
GO:0005070
TAS
Genome ProjectSH3/SH2 adaptor activity
GO:0005158
IBA
IEA
Genome Projectinsulin receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043548
IBA
Genome Projectphosphatidylinositol 3-kinase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IBA
Genome Projectcytosol
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001849Pleckstrin homology domain
IPR002404IRS-type PTB domain
IPR011993PH domain-like

No MapMan annotations defined for this gene.