Gene: ENSG00000133048 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000133048
Transcript Identifier
ENST00000255409
Gene Type
Coding gene
Location
1 : 203179445-203186623 : negative

Family Information

Homologous gene family
HOM03P001514
(49 genes in 12 species)
specific family
Orthologous gene family
ORTHO03P046123
(2 genes in 1 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
chitinase 3-like 1 (cartilage glycoprotein-39)

Identifiers

Type Value
pidENSP00000255409
HGNC1932
UniprotP36222
UniprotA0A024R969

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0006032
IBA
IEA
Genome Projectchitin catabolic process
GO:0006954
IEP
IEA
Genome Projectinflammatory response
GO:0007250
ISS
IEA
Genome Projectactivation of NF-kappaB-inducing kinase activity
GO:0010800
ISS
IEA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0045766
IMP
IEA
Genome Projectpositive regulation of angiogenesis
GO:0071347
IEA
Genome Projectcellular response to interleukin-1
GO:0071356
ISS
IEA
Genome Projectcellular response to tumor necrosis factor
GO:0072606
ISS
IEA
Genome Projectinterleukin-8 secretion
GO:0006915
IEA
Genome Projectapoptotic process
GO:0009612
IEP
Genome Projectresponse to mechanical stimulus
GO:0030324
IMP
Genome Projectlung development
GO:0034612
IEP
Genome Projectresponse to tumor necrosis factor
GO:0051216
NAS
Genome Projectcartilage development
GO:0051897
IMP
Genome Projectpositive regulation of protein kinase B signaling
GO:0070374
IMP
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070555
IEP
Genome Projectresponse to interleukin-1
GO:0070741
IEP
Genome Projectresponse to interleukin-6

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004553
IEA
Genome Projecthydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004568
IDA
IEA
Genome Projectchitinase activity
GO:0008061
IDA
IEA
Genome Projectchitin binding
GO:0005201
NAS
Genome Projectextracellular matrix structural constituent
GO:0030246
IEA
Genome Projectcarbohydrate binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005783
ISS
IEA
Genome Projectendoplasmic reticulum
GO:0005576
IBA
IEA
Genome Projectextracellular region
GO:0005578
NAS
Genome Projectproteinaceous extracellular matrix
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001223Glycoside hydrolase family 18, catalytic domain
IPR011583Chitinase II
IPR013781Glycoside hydrolase, catalytic domain
IPR017853Glycoside hydrolase superfamily
IPR028538Chitinase-3-like protein 1
IPR029070Chitinase insertion domain

No MapMan annotations defined for this gene.