Gene: ENSG00000133019 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000133019
Transcript Identifier
ENST00000615928
Gene Type
Coding gene
Location
1 : 239907452-239909224 : positive

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P028391
(4 genes in 4 species)
specific family

Descriptions

gene_descr
cholinergic receptor, muscarinic 3

Identifiers

Type Value
pidENSP00000482377
HGNC1952
UniprotP20309
UniprotA0A024R3S2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003056
IBA
IEA
Genome Projectregulation of vascular smooth muscle contraction
GO:0006939
IEA
Genome Projectsmooth muscle contraction
GO:0007165
TAS, IEA
Genome Projectsignal transduction
GO:0007186
TAS, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007213
ISS
IEA
Genome ProjectG-protein coupled acetylcholine receptor signaling pathway
GO:0007586
IEA
Genome Projectdigestion
GO:0019229
IEA
Genome Projectregulation of vasoconstriction
GO:0045987
IEA
Genome Projectpositive regulation of smooth muscle contraction
GO:0046541
IEA
Genome Projectsaliva secretion
GO:0006112
TAS
Genome Projectenergy reserve metabolic process
GO:0006464
TAS
Genome Projectcellular protein modification process
GO:0007197
IBA
Genome Projectadenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
GO:0007207
IBA
Genome Projectphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0007271
IBA
Genome Projectsynaptic transmission, cholinergic
GO:0007399
TAS
Genome Projectnervous system development
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0008283
TAS
Genome Projectcell proliferation
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0050796
TAS
Genome Projectregulation of insulin secretion
GO:0010579
IBA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0008144
IEA
Genome Projectdrug binding
GO:0016907
ISS
TAS, IEA
Genome ProjectG-protein coupled acetylcholine receptor activity
GO:0042166
ISS
IEA
Genome Projectacetylcholine binding
GO:0004435
TAS
Genome Projectphosphatidylinositol phospholipase C activity
GO:0004872
TAS
Genome Projectreceptor activity
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
ISS
TAS, IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IEA
Genome Projectdendrite
GO:0032279
IEA
Genome Projectasymmetric synapse
GO:0043679
IEA
Genome Projectaxon terminus
GO:0045202
IBA
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0016323
IEA
Genome Projectbasolateral plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000995Muscarinic acetylcholine receptor family
IPR001183Muscarinic acetylcholine receptor M3
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.