Gene: ENSG00000132693 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000132693
Transcript Identifier
ENST00000255030
Gene Type
Coding gene
Location
1 : 159713525-159714485 : negative

Family Information

Homologous gene family
HOM03P014219
(6 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P076295
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
C-reactive protein, pentraxin-related

Identifiers

Type Value
pidENSP00000255030
HGNC2367
UniprotP02741

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006953
TAS, IEA
Genome Projectacute-phase response
GO:0006954
TAS
Genome Projectinflammatory response
GO:0008228
TAS
Genome Projectopsonization
GO:0010628
IDA
Genome Projectpositive regulation of gene expression
GO:0010745
IDA
Genome Projectnegative regulation of macrophage derived foam cell differentiation
GO:0010888
IDA
Genome Projectnegative regulation of lipid storage
GO:0032930
IDA
Genome Projectpositive regulation of superoxide anion generation
GO:0045908
IDA, IMP
Genome Projectnegative regulation of vasodilation
GO:0050830
TAS
Genome Projectdefense response to Gram-positive bacterium
GO:2000482
IDA
Genome Projectregulation of interleukin-8 secretion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001849
IDA
Genome Projectcomplement component C1q binding
GO:0005509
IDA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0030169
IDA
Genome Projectlow-density lipoprotein particle binding
GO:0033265
TAS
Genome Projectcholine binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0050750
IPI
Genome Projectlow-density lipoprotein particle receptor binding
GO:0046790
IDA
Genome Projectvirion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
NAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
Genome Projectextracellular space
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001759Pentaxin-related
IPR013320Concanavalin A-like lectin/glucanase domain
IPR030476Pentaxin, conserved site

No MapMan annotations defined for this gene.