Gene: ENSG00000132688 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000132688
Transcript Identifier
ENST00000368223
Gene Type
Coding gene
Location
1 : 156669322-156677264 : negative

Family Information

Homologous gene family
HOM03P024231
(3 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
nestin

Identifiers

Type Value
pidENSP00000357206
HGNC7756
UniprotP48681

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000086
IDA
Genome ProjectG2/M transition of mitotic cell cycle
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007399
IEA
Genome Projectnervous system development
GO:0007417
NAS
Genome Projectcentral nervous system development
GO:0007420
ISS
Genome Projectbrain development
GO:0030844
ISS
Genome Projectpositive regulation of intermediate filament depolymerization
GO:0031076
ISS
Genome Projectembryonic camera-type eye development
GO:0032091
IDA
Genome Projectnegative regulation of protein binding
GO:0043086
IDA
Genome Projectnegative regulation of catalytic activity
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0048858
IEA
Genome Projectcell projection morphogenesis
GO:0072089
IMP
Genome Projectstem cell proliferation
GO:2000179
ISS
Genome Projectpositive regulation of neural precursor cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003674
ND
Genome Projectmolecular_function
GO:0005198
IEA
Genome Projectstructural molecule activity
GO:0019215
ISS
Genome Projectintermediate filament binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005882
NAS, IEA
Genome Projectintermediate filament
GO:0045111
IDA
Genome Projectintermediate filament cytoskeleton

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001664Intermediate filament protein
IPR018039Intermediate filament protein, conserved site
IPR031211Nestin

No MapMan annotations defined for this gene.