Gene: ENSG00000132109 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000132109
Transcript Identifier
ENST00000254436
Gene Type
Coding gene
Location
11 : 4385285-4390409 : negative

Family Information

Homologous gene family
HOM03P000320
(129 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P071733
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
tripartite motif containing 21

Identifiers

Type Value
pidENSP00000254436
HGNC11312
UniprotP19474

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000209
IDA
Genome Projectprotein polyubiquitination
GO:0006513
IDA
Genome Projectprotein monoubiquitination
GO:0007049
IEA
Genome Projectcell cycle
GO:0016567
IDA
IEA
Genome Projectprotein ubiquitination
GO:0019221
TAS
Genome Projectcytokine-mediated signaling pathway
GO:0031648
IMP
Genome Projectprotein destabilization
GO:0032088
IDA
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0032479
TAS
Genome Projectregulation of type I interferon production
GO:0032481
TAS
Genome Projectpositive regulation of type I interferon production
GO:0032897
IDA
Genome Projectnegative regulation of viral transcription
GO:0045087
IDA
TAS
Genome Projectinnate immune response
GO:0045787
IMP
Genome Projectpositive regulation of cell cycle
GO:0046598
IEA
Genome Projectpositive regulation of viral entry into host cell
GO:0051091
IDA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051865
IDA
Genome Projectprotein autoubiquitination
GO:0060333
TAS
Genome Projectinterferon-gamma-mediated signaling pathway
GO:0070206
IDA
Genome Projectprotein trimerization
GO:0090086
IMP
Genome Projectnegative regulation of protein deubiquitination
GO:1902187
IDA
Genome Projectnegative regulation of viral release from host cell

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0004842
IDA
Genome Projectubiquitin-protein transferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016874
IEA
Genome Projectligase activity
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000932
IEA
Genome Projectcytoplasmic mRNA processing body
GO:0005622
IEA
Genome Projectintracellular
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0030529
TAS, IEA
Genome Projectintracellular ribonucleoprotein complex
GO:0019005
IDA
Genome ProjectSCF ubiquitin ligase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000315B-box-type zinc finger
IPR001841Zinc finger, RING-type
IPR001870B30.2/SPRY domain
IPR003877SPRY domain
IPR003879Butyrophylin-like
IPR006574SPRY-associated
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR013320Concanavalin A-like lectin/glucanase domain
IPR017907Zinc finger, RING-type, conserved site
IPR020457Zinc finger, B-box, chordata

No MapMan annotations defined for this gene.