Gene: ENSG00000131828 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000131828
Transcript Identifier
ENST00000379806
Gene Type
Coding gene
Location
X : 19344038-19359653 : positive

Family Information

Homologous gene family
HOM03P000332
(126 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000469
(49 genes in 39 species)
specific family

Descriptions

gene_descr
pyruvate dehydrogenase (lipoamide) alpha 1

Identifiers

Type Value
pidENSP00000369134
HGNC8806
UniprotP08559

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0006006
IEA
Genome Projectglucose metabolic process
GO:0006086
IDA
Genome Projectacetyl-CoA biosynthetic process from pyruvate
GO:0006090
TAS
Genome Projectpyruvate metabolic process
GO:0006096
IEA
Genome Projectglycolytic process
GO:0006099
IDA
IEA
Genome Projecttricarboxylic acid cycle
GO:0008152
IEA
Genome Projectmetabolic process
GO:0010510
TAS
Genome Projectregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0044237
TAS
Genome Projectcellular metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0055114
IEA
Genome Projectoxidation-reduction process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004738
IDA
Genome Projectpyruvate dehydrogenase activity
GO:0004739
IEA
Genome Projectpyruvate dehydrogenase (acetyl-transferring) activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016624
IEA
Genome Projectoxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005739
IDA
TAS, IEA
Genome Projectmitochondrion
GO:0005759
TAS, IEA
Genome Projectmitochondrial matrix
GO:0043209
IEA
Genome Projectmyelin sheath
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0045254
IDA
Genome Projectpyruvate dehydrogenase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001017Dehydrogenase, E1 component
IPR017597Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y
IPR029061Thiamin diphosphate-binding fold

No MapMan annotations defined for this gene.