Gene: ENSG00000131203 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000131203
Transcript Identifier
ENST00000518237
Gene Type
Coding gene
Location
8 : 39913923-39928185 : positive

Family Information

Homologous gene family
HOM03P006236
(14 genes in 10 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
indoleamine 2,3-dioxygenase 1

Identifiers

Type Value
pidENSP00000430950
HGNC6059
UniprotP14902

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002534
IEA
Genome Projectcytokine production involved in inflammatory response
GO:0002666
IEA
Genome Projectpositive regulation of T cell tolerance induction
GO:0002678
IEA
Genome Projectpositive regulation of chronic inflammatory response
GO:0002830
IEA
Genome Projectpositive regulation of type 2 immune response
GO:0006569
TAS
Genome Projecttryptophan catabolic process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007565
TAS
Genome Projectfemale pregnancy
GO:0019441
IEA
Genome Projecttryptophan catabolic process to kynurenine
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032693
IEA
Genome Projectnegative regulation of interleukin-10 production
GO:0032735
IEA
Genome Projectpositive regulation of interleukin-12 production
GO:0033555
IEA
Genome Projectmulticellular organismal response to stress
GO:0034276
IEA
Genome Projectkynurenic acid biosynthetic process
GO:0034641
TAS
Genome Projectcellular nitrogen compound metabolic process
GO:0036269
IEA
Genome Projectswimming behavior
GO:0042130
IEA
Genome Projectnegative regulation of T cell proliferation
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0070233
IEA
Genome Projectnegative regulation of T cell apoptotic process
GO:0070234
IMP
Genome Projectpositive regulation of T cell apoptotic process
GO:0046006
IMP
Genome Projectregulation of activated T cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004833
EXP
Genome Projecttryptophan 2,3-dioxygenase activity
GO:0009055
TAS
Genome Projectelectron carrier activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0020037
IEA
Genome Projectheme binding
GO:0033754
IMP
IEA
Genome Projectindoleamine 2,3-dioxygenase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051213
IEA
Genome Projectdioxygenase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0030485
IEA
Genome Projectsmooth muscle contractile fiber
GO:0032421
IEA
Genome Projectstereocilium bundle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000898Indoleamine 2,3-dioxygenase

No MapMan annotations defined for this gene.