Gene: ENSG00000130702 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000130702
Transcript Identifier
ENST00000252999
Gene Type
Coding gene
Location
20 : 62309336-62367245 : negative

Family Information

Homologous gene family
HOM03P001010
(61 genes in 12 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
laminin, alpha 5

Identifiers

Type Value
pidENSP00000252999
HGNC6485
UniprotO15230

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
NAS
Genome Projectangiogenesis
GO:0001658
IEA
Genome Projectbranching involved in ureteric bud morphogenesis
GO:0001738
IEA
Genome Projectmorphogenesis of a polarized epithelium
GO:0001755
IEA
Genome Projectneural crest cell migration
GO:0001942
IEA
Genome Projecthair follicle development
GO:0007010
NAS
Genome Projectcytoskeleton organization
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007229
IMP
Genome Projectintegrin-mediated signaling pathway
GO:0007517
IEA
Genome Projectmuscle organ development
GO:0008037
NAS
Genome Projectcell recognition
GO:0008283
NAS
Genome Projectcell proliferation
GO:0009790
NAS
Genome Projectembryo development
GO:0009887
IEA
Genome Projectorgan morphogenesis
GO:0016331
IEA
Genome Projectmorphogenesis of embryonic epithelium
GO:0016477
IDA
Genome Projectcell migration
GO:0022617
TAS
Genome Projectextracellular matrix disassembly
GO:0030154
NAS
Genome Projectcell differentiation
GO:0030155
IEA
Genome Projectregulation of cell adhesion
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0030324
IEA
Genome Projectlung development
GO:0030334
IEA
Genome Projectregulation of cell migration
GO:0034446
IDA
Genome Projectsubstrate adhesion-dependent cell spreading
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0042384
IEA
Genome Projectcilium assembly
GO:0042475
IEA
Genome Projectodontogenesis of dentin-containing tooth
GO:0045446
NAS
Genome Projectendothelial cell differentiation
GO:0045995
IEA
Genome Projectregulation of embryonic development
GO:0048041
NAS
Genome Projectfocal adhesion assembly
GO:0048754
IEA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0060445
IEA
Genome Projectbranching involved in salivary gland morphogenesis
GO:0090002
IEA
Genome Projectestablishment of protein localization to plasma membrane

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005178
IDA
Genome Projectintegrin binding
GO:0005198
IC
Genome Projectstructural molecule activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005578
IEA
Genome Projectproteinaceous extracellular matrix
GO:0005604
IDA
IEA
Genome Projectbasement membrane
GO:0005605
NAS, IEA
Genome Projectbasal lamina
GO:0005610
IEA
Genome Projectlaminin-5 complex
GO:0005615
IDA
Genome Projectextracellular space
GO:0005634
IDA
Genome Projectnucleus
GO:0031012
IDA
Genome Projectextracellular matrix
GO:0043259
IDA
TAS
Genome Projectlaminin-10 complex
GO:0043260
TAS
Genome Projectlaminin-11 complex
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000034Laminin IV
IPR001368TNFR/NGFR cysteine-rich region
IPR001791Laminin G domain
IPR002049Laminin EGF domain
IPR008211Laminin, N-terminal
IPR009254Laminin alpha, domain I
IPR010307Laminin domain II
IPR013320Concanavalin A-like lectin/glucanase domain

No MapMan annotations defined for this gene.