Gene: ENSG00000130649 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000130649
Transcript Identifier
ENST00000252945
Gene Type
Coding gene
Location
10 : 133527396-133538964 : positive

Family Information

Homologous gene family
HOM03P000006
(1609 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000349
(53 genes in 5 species)
specific family

Descriptions

gene_descr
cytochrome P450, family 2, subfamily E, polypeptide 1

Identifiers

Type Value
pidENSP00000252945
HGNC2631
UniprotP05181

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006641
IEA
Genome Projecttriglyceride metabolic process
GO:0006805
IBA
TAS
Genome Projectxenobiotic metabolic process
GO:0008202
IMP
Genome Projectsteroid metabolic process
GO:0010193
IEA
Genome Projectresponse to ozone
GO:0010243
IEA
Genome Projectresponse to organonitrogen compound
GO:0016098
IDA
Genome Projectmonoterpenoid metabolic process
GO:0017144
IDA, IMP
Genome Projectdrug metabolic process
GO:0019373
IBA
Genome Projectepoxygenase P450 pathway
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042738
IBA
Genome Projectexogenous drug catabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0046483
IDA
Genome Projectheterocycle metabolic process
GO:0055114
IDA
IEA
Genome Projectoxidation-reduction process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004497
IDA
TAS, IEA
Genome Projectmonooxygenase activity
GO:0005506
IEA
Genome Projectiron ion binding
GO:0008392
IBA
Genome Projectarachidonic acid epoxygenase activity
GO:0008395
IBA
Genome Projectsteroid hydroxylase activity
GO:0016491
IDA
IEA
Genome Projectoxidoreductase activity
GO:0016705
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016709
TAS, IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0016712
IBA
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019825
TAS
Genome Projectoxygen binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0020037
IDA
IEA
Genome Projectheme binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0005737
IBA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
TAS, IEA
Genome Projectendoplasmic reticulum membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0031090
IEA
Genome Projectorganelle membrane
GO:0031227
IEA
Genome Projectintrinsic component of endoplasmic reticulum membrane
GO:0043231
IBA
IEA
Genome Projectintracellular membrane-bounded organelle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001128Cytochrome P450
IPR002401Cytochrome P450, E-class, group I
IPR008070Cytochrome P450, E-class, group I, CYP2E-like
IPR017972Cytochrome P450, conserved site

No MapMan annotations defined for this gene.