Gene: ENSG00000129521 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000129521
Transcript Identifier
ENST00000250457
Gene Type
Coding gene
Location
14 : 33925891-33950752 : negative

Family Information

Homologous gene family
HOM03P003570
(27 genes in 15 species)
specific family
Orthologous gene family
ORTHO03P064088
(2 genes in 2 species)
specific family

Descriptions

gene_descr
egl-9 family hypoxia-inducible factor 3

Identifiers

Type Value
pidENSP00000250457
HGNC14661
UniprotQ9H6Z9

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEP
Genome Projectresponse to hypoxia
GO:0006915
IEP
IEA
Genome Projectapoptotic process
GO:0006919
IEP
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0018126
IDA
Genome Projectprotein hydroxylation
GO:0018401
IDA
Genome Projectpeptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0042127
IEP
Genome Projectregulation of cell proliferation
GO:0043523
ISS
Genome Projectregulation of neuron apoptotic process
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0061418
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456
TAS
Genome Projectcellular response to hypoxia

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005506
IEA
Genome Projectiron ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016705
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706
IDA
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418
IEA
Genome ProjectL-ascorbic acid binding
GO:0031545
IDA
Genome Projectpeptidyl-proline 4-dioxygenase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051213
IEA
Genome Projectdioxygenase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR005123Oxoglutarate/iron-dependent dioxygenase
IPR006620Prolyl 4-hydroxylase, alpha subunit

No MapMan annotations defined for this gene.