Gene: ENSG00000129473 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000129473
Transcript Identifier
ENST00000250405
Gene Type
Coding gene
Location
14 : 23307768-23308965 : positive

Family Information

Homologous gene family
HOM03P011025
(7 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P069236
(2 genes in 2 species)
specific family

Descriptions

gene_descr
BCL2-like 2

Identifiers

Type Value
pidENSP00000250405
HGNC995
UniprotQ92843

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007283
TAS
Genome Projectspermatogenesis
GO:0008630
IBA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043066
IMP
TAS
Genome Projectnegative regulation of apoptotic process
GO:0060011
IEA
Genome ProjectSertoli cell proliferation
GO:0097192
IBA
IEA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:2001243
IBA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0042803
IBA
Genome Projectprotein homodimerization activity
GO:0046982
IBA
IEA
Genome Projectprotein heterodimerization activity
GO:0051400
IEA
Genome ProjectBH domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005741
IBA
Genome Projectmitochondrial outer membrane
GO:0005829
IEA
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane
GO:0031966
IEA
Genome Projectmitochondrial membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002475Bcl2-like
IPR003093Apoptosis regulator, Bcl-2 protein, BH4
IPR013280Apoptosis regulator, Bcl-W
IPR020717Apoptosis regulator, Bcl-2, BH1 motif, conserved site
IPR020726Apoptosis regulator, Bcl-2, BH2 motif, conserved site
IPR020731Apoptosis regulator, Bcl-2, BH4 motif, conserved site
IPR026298Blc2 family

No MapMan annotations defined for this gene.