Gene: ENSG00000128918 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000128918
Transcript Identifier
ENST00000249750
Gene Type
Coding gene
Location
15 : 57955197-58065650 : negative

Family Information

Homologous gene family
HOM03P000067
(383 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000296
(56 genes in 25 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
aldehyde dehydrogenase 1 family, member A2

Identifiers

Type Value
pidENSP00000249750
HGNC15472
UniprotO94788

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001568
IEA
Genome Projectblood vessel development
GO:0001822
IEA
Genome Projectkidney development
GO:0001889
IEA
Genome Projectliver development
GO:0001936
IEA
Genome Projectregulation of endothelial cell proliferation
GO:0002138
IEA
Genome Projectretinoic acid biosynthetic process
GO:0003007
IEA
Genome Projectheart morphogenesis
GO:0006776
NAS
Genome Projectvitamin A metabolic process
GO:0007494
IEA
Genome Projectmidgut development
GO:0008152
IEA
Genome Projectmetabolic process
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IDA
Genome Projectnegative regulation of cell proliferation
GO:0009855
IEA
Genome Projectdetermination of bilateral symmetry
GO:0009952
IEA
Genome Projectanterior/posterior pattern specification
GO:0009954
IEA
Genome Projectproximal/distal pattern formation
GO:0010628
IEA
Genome Projectpositive regulation of gene expression
GO:0014032
IEA
Genome Projectneural crest cell development
GO:0016331
IEA
Genome Projectmorphogenesis of embryonic epithelium
GO:0021915
IMP
Genome Projectneural tube development
GO:0021983
IEA
Genome Projectpituitary gland development
GO:0030182
IEA
Genome Projectneuron differentiation
GO:0030324
IEA
Genome Projectlung development
GO:0030326
IEA
Genome Projectembryonic limb morphogenesis
GO:0030900
IEA
Genome Projectforebrain development
GO:0030902
IEA
Genome Projecthindbrain development
GO:0031016
IEA
Genome Projectpancreas development
GO:0031076
IEA
Genome Projectembryonic camera-type eye development
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0033189
IEA
Genome Projectresponse to vitamin A
GO:0034097
IDA
Genome Projectresponse to cytokine
GO:0035115
IEA
Genome Projectembryonic forelimb morphogenesis
GO:0035799
IEA
Genome Projectureter maturation
GO:0042572
IEA
Genome Projectretinol metabolic process
GO:0042573
ISS
IEA
Genome Projectretinoic acid metabolic process
GO:0042574
IEA
Genome Projectretinal metabolic process
GO:0042904
IEA
Genome Project9-cis-retinoic acid biosynthetic process
GO:0043010
IEA
Genome Projectcamera-type eye development
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0048384
IEA
Genome Projectretinoic acid receptor signaling pathway
GO:0048566
IEA
Genome Projectembryonic digestive tract development
GO:0048738
IEA
Genome Projectcardiac muscle tissue development
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0060324
IEA
Genome Projectface development
GO:0071300
IEA
Genome Projectcellular response to retinoic acid

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001758
ISS, IBA
IEA
Genome Projectretinal dehydrogenase activity
GO:0004028
ISS, IBA
IEA
Genome Project3-chloroallyl aldehyde dehydrogenase activity
GO:0004029
IBA
Genome Projectaldehyde dehydrogenase (NAD) activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016620
IEA
Genome Projectoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0016918
ISS
IEA
Genome Projectretinal binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR015590Aldehyde dehydrogenase domain
IPR016160Aldehyde dehydrogenase, cysteine active site
IPR016161Aldehyde/histidinol dehydrogenase
IPR016162Aldehyde dehydrogenase N-terminal domain
IPR016163Aldehyde dehydrogenase, C-terminal
IPR029510Aldehyde dehydrogenase, glutamic acid active site

No MapMan annotations defined for this gene.