Gene: ENSG00000127334 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000127334
Transcript Identifier
ENST00000344096
Gene Type
Coding gene
Location
12 : 67649134-67658713 : positive

Family Information

Homologous gene family
HOM03P000009
(1563 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P002594
(29 genes in 21 species)
specific family

Descriptions

gene_descr
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

Identifiers

Type Value
pidENSP00000342105
HGNC3093
UniprotQ92630

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IDA
TAS, IEA
Genome Projectprotein phosphorylation
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006974
IEP
Genome Projectcellular response to DNA damage stimulus
GO:0007224
IMP
Genome Projectsmoothened signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018108
IDA
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0042771
IDA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0045725
IDA
Genome Projectpositive regulation of glycogen biosynthetic process
GO:0051534
IMP
Genome Projectnegative regulation of NFAT protein import into nucleus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0000287
IDA
Genome Projectmagnesium ion binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004712
IEA
Genome Projectprotein serine/threonine/tyrosine kinase activity
GO:0004713
IDA
IEA
Genome Projectprotein tyrosine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IDA
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0030145
IDA
Genome Projectmanganese ion binding
GO:0043130
IDA
Genome Projectubiquitin binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000151
IDA
Genome Projectubiquitin ligase complex
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
IDA
TAS, IEA
Genome Projectcytoplasm
GO:0030529
IEA
Genome Projectintracellular ribonucleoprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.