Gene: ENSG00000126353 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000126353
Transcript Identifier
ENST00000246657
Gene Type
Coding gene
Location
17 : 40554742-40565409 : negative

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P067707
(2 genes in 2 species)
specific family

Descriptions

gene_descr
chemokine (C-C motif) receptor 7

Identifiers

Type Value
pidENSP00000246657
HGNC1608
UniprotP32248
UniprotA0N0Q0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002606
ISS
IEA
Genome Projectpositive regulation of dendritic cell antigen processing and presentation
GO:0002885
ISS
IEA
Genome Projectpositive regulation of hypersensitivity
GO:0002922
ISS
IEA
Genome Projectpositive regulation of humoral immune response
GO:0006935
IEA
Genome Projectchemotaxis
GO:0006954
NAS, IEA
Genome Projectinflammatory response
GO:0006955
IEA
Genome Projectimmune response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
TAS, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032649
ISS
IEA
Genome Projectregulation of interferon-gamma production
GO:0032735
ISS
IEA
Genome Projectpositive regulation of interleukin-12 production
GO:0045060
IEA
Genome Projectnegative thymic T cell selection
GO:0050706
ISS
IEA
Genome Projectregulation of interleukin-1 beta secretion
GO:0050862
IEA
Genome Projectpositive regulation of T cell receptor signaling pathway
GO:0070098
ISS
IEA
Genome Projectchemokine-mediated signaling pathway
GO:0072610
ISS
IEA
Genome Projectinterleukin-12 secretion
GO:0097029
ISS
IEA
Genome Projectmature conventional dendritic cell differentiation
GO:2000510
ISS
IEA
Genome Projectpositive regulation of dendritic cell chemotaxis
GO:2000522
ISS
IEA
Genome Projectpositive regulation of immunological synapse formation
GO:2000525
ISS
IEA
Genome Projectpositive regulation of T cell costimulation
GO:2000526
ISS
IEA
Genome Projectpositive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
GO:0001768
IC
Genome Projectestablishment of T cell polarity
GO:0001954
IC
Genome Projectpositive regulation of cell-matrix adhesion
GO:0002407
IC
Genome Projectdendritic cell chemotaxis
GO:0002408
IDA
IC
Genome Projectmyeloid dendritic cell chemotaxis
GO:0007204
TAS
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0030838
IC
Genome Projectpositive regulation of actin filament polymerization
GO:0031274
IC
Genome Projectpositive regulation of pseudopodium assembly
GO:0031529
IC
Genome Projectruffle organization
GO:0034695
IC
Genome Projectresponse to prostaglandin E
GO:0038115
IDA
Genome Projectchemokine (C-C motif) ligand 19 signaling pathway
GO:0038116
IDA
Genome Projectchemokine (C-C motif) ligand 21 signaling pathway
GO:0043123
IC
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043552
IC
Genome Projectpositive regulation of phosphatidylinositol 3-kinase activity
GO:0045785
IC
Genome Projectpositive regulation of cell adhesion
GO:0045860
IC
Genome Projectpositive regulation of protein kinase activity
GO:0046330
IC
Genome Projectpositive regulation of JNK cascade
GO:0051209
IC
Genome Projectrelease of sequestered calcium ion into cytosol
GO:0051491
IC
Genome Projectpositive regulation of filopodium assembly
GO:0051897
IC
Genome Projectpositive regulation of protein kinase B signaling
GO:0070374
IC
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071345
IDA
Genome Projectcellular response to cytokine stimulus
GO:0071731
IC
Genome Projectresponse to nitric oxide
GO:0090023
IDA
Genome Projectpositive regulation of neutrophil chemotaxis
GO:0090630
IC
Genome Projectactivation of GTPase activity
GO:0097022
TAS
Genome Projectlymphocyte migration into lymph node
GO:2000107
IC
Genome Projectnegative regulation of leukocyte apoptotic process
GO:2000147
IC
Genome Projectpositive regulation of cell motility
GO:2000547
ISS
Genome Projectregulation of dendritic cell dendrite assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
TAS, IEA
Genome ProjectG-protein coupled receptor activity
GO:0004950
IEA
Genome Projectchemokine receptor activity
GO:0016493
ISS
IEA
Genome ProjectC-C chemokine receptor activity
GO:0035757
IPI
Genome Projectchemokine (C-C motif) ligand 19 binding
GO:0035758
IPI
Genome Projectchemokine (C-C motif) ligand 21 binding
GO:0038117
IDA
Genome ProjectC-C motif chemokine 19 receptor activity
GO:0038121
IDA
Genome ProjectC-C motif chemokine 21 receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009897
IEA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0005622
IDA
Genome Projectintracellular
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0009986
IDA
Genome Projectcell surface

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000355Chemokine receptor family
IPR001718CC chemokine receptor 7
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.